Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | PPIA | P62937 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4675867 | 0.83 | TSHR (0.38) | TSHRPTPN1ALDH1A1BLMACHE | |
| SCHEMBL3019526 | 0.83 | TSHR (0.38) | TSHRPTPN1ALDH1A1BLMACHE | |
| SCHEMBL5481247 | 0.81 | TSHR (0.44) | TSHRALDH1A1BLMACHECYP19A1 | |
| SCHEMBL9954635 | 0.81 | TSHR (0.44) | TSHRALDH1A1BLMACHECYP19A1 | |
| SCHEMBL28997257 | 0.81 | TSHR (0.44) | TSHRALDH1A1BLMACHECYP19A1 | |
| SCHEMBL10529481 | 0.81 | TSHR (0.44) | TSHRALDH1A1BLMACHECYP19A1 | |
| SCHEMBL9956396 | 0.81 | TSHR (0.44) | TSHRALDH1A1BLMACHECYP19A1 | |
| SCHEMBL9956309 | 0.81 | TSHR (0.44) | TSHRALDH1A1BLMACHECYP19A1 | |
| SCHEMBL9954983 | 0.81 | TSHR (0.44) | TSHRALDH1A1BLMACHECYP19A1 | |
| SCHEMBL9954521 | 0.81 | TSHR (0.44) | TSHRALDH1A1BLMACHECYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850928-B1 | Novel peroxyoxalates derived from hydroxy-hydroperoxides | ATOFINA CHEM INC (US) | 2001-10-31 | — | — | EP | disclosed |
| US-5981787-A | INITIATORS FOR POLYMERIZING ETHYLENICALLY UNSATURATED MONOMERS AND FOR CURING OF UNSATURATED POLYESTER RESINS | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1999-11-09 | — | — | US | disclosed |
| EP-0850928-A1 | Novel peroxyoxalates derived from hydroxy-hydroperoxides | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1998-07-01 | — | — | EP | disclosed |