SCHEMBL7783293

SCHEMBL7783293

CCCc1ccc(/C=N/N=C\c2ccc(OC(F)(F)F)cc2)c(F)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GCGR P47871 1/20 0.36
TSHR P16473 1/20 0.36
PDE2A O00408 2/20 0.36
BACE1 P56817 3/20 0.35
BCHE P06276 2/20 0.35
ACHE P22303 2/20 0.35
MCHR1 Q99705 1/20 0.35
PCSK9 Q8NBP7 1/20 0.35
SLC6A4 P31645 2/20 0.34
GPR84 Q9NQS5 1/20 0.34
TRPV1 Q8NER1 2/20 0.34
MEN1 O00255 1/20 0.34
NPC1 O15118 1/20 0.34
MITF O75030 1/20 0.34
GAA P10253 1/20 0.34
RAB9A P51151 1/20 0.34
KMT2A Q03164 1/20 0.34
ALDH1A1 P00352 1/20 0.33
DAO P14920 1/20 0.33
CTSD P07339 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7783294 1.00 GCGR (0.36) GCGRTSHRPDE2ABACE1BCHE
SCHEMBL7793066 0.93 PCSK9 (0.42) GCGRTSHRPDE2ABACE1BCHE
SCHEMBL7793060 0.93 PCSK9 (0.42) GCGRTSHRPDE2ABACE1BCHE
SCHEMBL7783363 0.92 PCSK9 (0.39) GCGRTSHRPDE2ABACE1BCHE
SCHEMBL7783368 0.92 PCSK9 (0.39) GCGRTSHRPDE2ABACE1BCHE
SCHEMBL7789948 0.91 TSHR (0.38) GCGRTSHRPDE2ABACE1BCHE
SCHEMBL7789946 0.91 TSHR (0.38) GCGRTSHRPDE2ABACE1BCHE
SCHEMBL7793190 0.91 PCSK9 (0.39) GCGRPCSK9
SCHEMBL7793194 0.91 PCSK9 (0.39) GCGRPCSK9
SCHEMBL7788553 0.87 TSHR (0.42) GCGRTSHRBACE1BCHEACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0825176-B1 Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same DAINIPPON INK & CHEMICALS (JP) 2001-11-14 EP disclosed
US-6010642-A LIGHT SCATTERING LIQUID CRYSTAL DISPLAY DAINIPPON INK AND CHEMICALS, INC. (JP) 2000-01-04 US disclosed
EP-0825176-A1 Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same DAINIPPON INK AND CHEMICALS, INC. (JP) 1998-02-25 EP disclosed