SCHEMBL7783460

SCHEMBL7783460

CCc1ccc(/C=N/N=C/c2cc(F)c(OCC(F)(F)F)c(F)c2)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
FFAR4 Q5NUL3 3/20 0.35
TUBB1 Q9H4B7 2/20 0.34
MAOA P21397 1/20 0.33
NPC1 O15118 3/20 0.33
GAA P10253 3/20 0.33
RAB9A P51151 2/20 0.33
PKM P14618 1/20 0.33
LMNA P02545 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
MAPT P10636 2/20 0.32
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
SPHK2 Q9NRA0 1/20 0.32
SPHK1 Q9NYA1 1/20 0.32
APP P05067 1/20 0.31
PPARG P37231 1/20 0.31
PPARD Q03181 1/20 0.31
PPARA Q07869 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7783461 1.00 MEN1 (0.35) MEN1KMT2AFFAR4TUBB1MAOA
SCHEMBL7788659 0.90 GRIN2D (0.36) MEN1KMT2AFFAR4NPC1RAB9A
SCHEMBL7788658 0.90 GRIN2D (0.36) MEN1KMT2AFFAR4NPC1RAB9A
SCHEMBL7792148 0.88 GRIN2D (0.45) MEN1KMT2A
SCHEMBL7792146 0.88 GRIN2D (0.45) MEN1KMT2A
SCHEMBL7792285 0.87 GRIN2D (0.41) MEN1KMT2ALMNAALDH1A1SPHK2
SCHEMBL7792289 0.87 GRIN2D (0.41) MEN1KMT2ALMNAALDH1A1SPHK2
SCHEMBL7793311 0.86 NPC1 (0.47) MEN1KMT2AFFAR4NPC1RAB9A
SCHEMBL7793307 0.86 NPC1 (0.47) MEN1KMT2AFFAR4NPC1RAB9A
SCHEMBL7788378 0.86 KMT2A (0.41) MEN1KMT2ATUBB1NPC1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0825176-B1 Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same DAINIPPON INK & CHEMICALS (JP) 2001-11-14 EP disclosed
US-6010642-A LIGHT SCATTERING LIQUID CRYSTAL DISPLAY DAINIPPON INK AND CHEMICALS, INC. (JP) 2000-01-04 US disclosed
EP-0825176-A1 Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same DAINIPPON INK AND CHEMICALS, INC. (JP) 1998-02-25 EP disclosed