Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 5/20 | 0.65 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | PGR | P06401 | 1/20 | 0.65 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.65 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | CBR1 | P16152 | 1/20 | 0.65 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.65 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.65 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.65 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2136172 | 0.82 | TTR (0.66) | TTRNR1I2LMNAPGRHSP90AA1 | |
| SCHEMBL3824447 | 0.82 | TTR (0.61) | TTRNR1I2LMNAPGRHSP90AA1 | |
| SCHEMBL29394087 | 0.82 | TTR (0.61) | TTRNR1I2LMNAPGRHSP90AA1 | |
| SCHEMBL29518952 | 0.82 | TTR (0.61) | TTRNR1I2LMNAPGRHSP90AA1 | |
| SCHEMBL10540653 | 0.82 | TTR (0.83) | TTRNR1I2LMNAPGRHSP90AA1 | |
| SCHEMBL10765474 | 0.81 | TTR (0.76) | TTRNR1I2LMNAPGRHSP90AA1 | |
| SCHEMBL23407743 | 0.80 | TTR (0.57) | TTRNR1I2LMNAPGRHSP90AA1 | |
| SCHEMBL23391591 | 0.80 | TTR (0.57) | TTRNR1I2LMNAPGRHSP90AA1 | |
| SCHEMBL30390614 | 0.79 | RHEB (0.44) | TTRNR1I2LMNAPGRHSP90AA1 | |
| SCHEMBL20241791 | 0.79 | RHEB (0.44) | TTRNR1I2LMNAPGRHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828475-B1 | PREPARATION OF A VISUALLY CLEAR GEL DENTIFRICE | COLGATE PALMOLIVE CO (US) | 2001-10-04 | — | — | EP | disclosed |
| EP-0549287-B1 | Visually clear gel dentifrice | COLGATE PALMOLIVE CO (US) | 1997-03-19 | — | — | EP | disclosed |
| US-5582816-A | ADDING TO SORBITOL LIQUID VEHICLE A SILICA POLISHING AGENT, A GELLING AGENT, ANIONIC POLYMER | COLGATE PALMOLIVE COMPANY (US) | 1996-12-10 | — | — | US | disclosed |
| US-5252313-A | Comprising water, sorbitol humectants and synthetic anionic copolymer; refractive index, clarity, stability | COLGATE-PALMOLIVE COMPANY (US) | 1993-10-12 | — | — | US | disclosed |
| EP-0549287-A1 | Visually clear gel dentifrice | Colgate-Palmolive Company (US) | 1993-06-30 | — | — | EP | disclosed |