Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | STS | P08842 | 1/20 | 0.52 |
| ▸ | JAK2 | O60674 | 1/20 | 0.52 |
| ▸ | JAK1 | P23458 | 1/20 | 0.52 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.51 |
| ▸ | PTPRB | P23467 | 1/20 | 0.50 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.50 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | YAP1 | P46937 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23249889 | 0.81 | SMN1; SMN2 (0.58) | MEN1KMT2AKDM4EPKMSTS | |
| SCHEMBL3837667 | 0.80 | MEN1 (0.61) | MEN1KMT2AKDM4EPKMSTS | |
| SCHEMBL652408 | 0.80 | MEN1 (0.57) | MEN1KMT2AKDM4EPKMSTS | |
| SCHEMBL7421811 | 0.80 | MEN1 (0.57) | MEN1KMT2AKDM4EPKMSTS | |
| SCHEMBL3012474 | 0.80 | JAK2 (0.62) | MEN1KMT2AKDM4EPKMSTS | |
| SCHEMBL803663 | 0.80 | JAK2 (0.54) | MEN1KMT2AKDM4EPKMSTS | |
| SCHEMBL2792425 | 0.79 | MEN1 (0.60) | MEN1KMT2AKDM4EPKMSTS | |
| SCHEMBL618193 | 0.79 | JAK2 (0.59) | MEN1KMT2AKDM4EPKMSTS | |
| SCHEMBL803527 | 0.79 | JAK2 (0.74) | MEN1KMT2AKDM4EPKMSTS | |
| SCHEMBL2374261 | 0.79 | SMN1; SMN2 (0.62) | KMT2AKDM4EPKMSTSJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6251918-B1 | FOR THERAPY OF STROKE, CEREBRAL ISCHEMIA, HEAD TRAUMA, OR EPILEPSY | WARNER-LAMBERT COMPANY | 2001-06-26 | — | — | US | disclosed |