Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 7/20 | 0.42 |
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.42 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.40 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.40 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10564674 | 0.98 | USP2 (0.53) | USP2ALDH1A1CNR1CNR2PLA2G2C | |
| SCHEMBL28854928 | 0.98 | USP2 (0.53) | USP2ALDH1A1CNR1CNR2PLA2G2C | |
| SCHEMBL11587919 | 0.95 | USP2 (0.50) | USP2ALDH1A1CNR1CNR2PLA2G2C | |
| SCHEMBL10816729 | 0.90 | LPAR1 (0.46) | USP2PLA2G2CLPAR1LPAR3LPAR2 | |
| SCHEMBL11302968 | 0.88 | LPAR1 (0.49) | USP2PLA2G2CLPAR1LPAR3LPAR2 | |
| SCHEMBL2524076 | 0.87 | CNR1 (0.51) | USP2ALDH1A1CNR1CNR2PLA2G2C | |
| SCHEMBL566245 | 0.87 | CNR1 (0.51) | USP2ALDH1A1CNR1CNR2PLA2G2C | |
| SCHEMBL2231650 | 0.83 | CNR1 (0.55) | USP2ALDH1A1CNR1CNR2PLA2G2C | |
| SCHEMBL2233827 | 0.83 | CNR1 (0.55) | USP2ALDH1A1CNR1CNR2PLA2G2C | |
| SCHEMBL2234079 | 0.83 | CNR1 (0.55) | USP2ALDH1A1CNR1CNR2PLA2G2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6252060-B1 | COMPLEX CONTAINING DIDEOXYGUANOSINE | NEXSTAR PHARMACEUTICALS, INC. | 2001-06-26 | — | — | US | claimed |
| US-5463092-A | Viricides | VESTAR, INC. (US) | 1995-10-31 | — | — | US | claimed |
| EP-0674646-B1 | LIPID DERIVATIVES OF PHOSPHONOACIDS FOR LIPOSOMAL INCORPORATION AND METHOD OF USE | CHIMERIX INC (US) | 2001-10-04 | — | — | EP | disclosed |
| US-5744461-A | VIRICIDES | NEXSTAR PHARMACEUTICALS, INC. (US) | 1998-04-28 | — | — | US | disclosed |
| EP-0674646-A4 | LIPID DERIVATIVES OF PHOSPHONOACIDS FOR LIPOSOMAL INCORPORATION AND METHOD OF USE. | VESTAR INC (US) | 1996-01-17 | — | — | EP | disclosed |
| US-5463092-A | Viricides | VESTAR, INC. (US) | 1995-10-31 | — | — | US | disclosed |
| EP-0674646-A1 | LIPID DERIVATIVES OF PHOSPHONOACIDS FOR LIPOSOMAL INCORPORATION AND METHOD OF USE | NeXstar Pharmaceuticals, Inc. (US) | 1995-10-04 | — | — | EP | disclosed |
| WO-1994013682-A1 | LIPID DERIVATIVES OF PHOSPHONOACIDS FOR LIPOSOMAL INCORPORATION AND METHOD OF USE | VESTAR, INC. (US) | 1994-06-23 | — | — | WO | disclosed |