Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27553437 | 1.00 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3POLBALDH1A1 | |
| SCHEMBL7785199 | 1.00 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3POLBALDH1A1 | |
| SCHEMBL7785494 | 0.81 | NPSR1 (0.47) | SLC6A2SLC6A4SLC6A3POLBALDH1A1 | |
| SCHEMBL7788974 | 0.81 | NPSR1 (0.47) | SLC6A2SLC6A4SLC6A3POLBALDH1A1 | |
| SCHEMBL27530382 | 0.81 | NPSR1 (0.47) | SLC6A2SLC6A4SLC6A3POLBALDH1A1 | |
| SCHEMBL7789190 | 0.81 | ACKR3 (0.41) | SLC6A2SLC6A4SLC6A3POLBALDH1A1 | |
| SCHEMBL7785718 | 0.81 | ACKR3 (0.41) | SLC6A2SLC6A4SLC6A3POLBALDH1A1 | |
| SCHEMBL7784989 | 0.80 | ACP3 (0.45) | ALDH1A1MEN1KMT2AMAPK1CYP3A4 | |
| SCHEMBL7780316 | 0.78 | ACP3 (0.49) | ALDH1A1MEN1KMT2ACYP3A4LMNA | |
| SCHEMBL7785096 | 0.78 | MEN1 (0.40) | SLC6A2SLC6A4SLC6A3POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| CN-1287117-A | Cyclobutene derivatives, preparation method and therapeutic use thereof | SANKYO CO (JP) | 2001-03-14 | — | — | CN | disclosed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |