Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 1/20 | 0.85 |
| ▸ | RNASEL | Q05823 | 6/20 | 0.75 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11776064 | 1.00 | ADORA1 (0.85) | ADORA1RNASELP2RY2 | |
| SCHEMBL23250438 | 0.99 | ADORA1 (0.84) | ADORA1RNASELP2RY2 | |
| SCHEMBL7706114 | 0.99 | ADORA1 (0.84) | ADORA1RNASELP2RY2 | |
| SCHEMBL23250436 | 0.99 | ADORA1 (0.84) | ADORA1RNASELP2RY2 | |
| SCHEMBL8167524 | 0.93 | ADORA1 (0.74) | ADORA1RNASELP2RY2 | |
| SCHEMBL29539212 | 0.93 | ADORA1 (0.74) | ADORA1RNASELP2RY2 | |
| SCHEMBL536567 | 0.93 | ADORA1 (0.73) | ADORA1RNASELP2RY2 | |
| SCHEMBL4370169 | 0.93 | ADORA1 (0.73) | ADORA1RNASELP2RY2 | |
| SCHEMBL30918598 | 0.93 | ADORA1 (0.73) | ADORA1RNASELP2RY2 | |
| SCHEMBL8509979 | 0.93 | ADORA1 (0.85) | ADORA1RNASELP2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6252060-B1 | COMPLEX CONTAINING DIDEOXYGUANOSINE | NEXSTAR PHARMACEUTICALS, INC. | 2001-06-26 | — | — | US | disclosed |
| US-5817638-A | USING HYBRID NUCLEOSIDES | NEXSTAR PHARMACEUTICALS, INC. (US) | 1998-10-06 | — | — | US | disclosed |
| EP-0594677-A4 | ANTIVIRAL LIPONUCLEOSIDES: TREATMENT OF HEPATITIS B | VICAL INC (US) | 1997-09-17 | — | — | EP | disclosed |
| EP-0594677-A1 | ANTIVIRAL LIPONUCLEOSIDES: TREATMENT OF HEPATITIS B | NeXstar Pharmaceuticals, Inc. (US) | 1994-05-04 | — | — | EP | disclosed |
| WO-1993000910-A1 | ANTIVIRAL LIPONUCLEOSIDES: TREATMENT OF HEPATITIS B | VICAL, INC. (US) | 1993-01-21 | — | — | WO | disclosed |