Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 13/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | CSNK1G1 | Q9HCP0 | 2/20 | 0.34 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.34 |
| ▸ | PRKX | P51817 | 1/20 | 0.34 |
| ▸ | NEK4 | P51957 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 1/20 | 0.34 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.34 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7785103 | 0.99 | MAPKAPK2 (0.40) | MAPKAPK2MAPK14CXCR2PDPK1AURKB | |
| SCHEMBL7780735 | 0.95 | MAPKAPK2 (0.38) | MAPKAPK2MAPK14CXCR2PDPK1TEAD4 | |
| SCHEMBL7789434 | 0.95 | MAPKAPK2 (0.38) | MAPKAPK2MAPK14CXCR2PDPK1TEAD4 | |
| Hydrochloric Acid SCHEMBL7803654 | 0.94 | MAPKAPK2 (0.37) | MAPKAPK2MAPK14CXCR2PDPK1TEAD4 | |
| SCHEMBL7784941 | 0.94 | S1PR3 (0.38) | MAPKAPK2MAPK14CXCR2 | |
| Hydrochloric Acid SCHEMBL7801963 | 0.94 | MAPKAPK2 (0.37) | MAPKAPK2MAPK14CXCR2PDPK1TEAD4 | |
| SCHEMBL7801400 | 0.94 | S1PR3 (0.38) | MAPKAPK2MAPK14CXCR2 | |
| SCHEMBL7785139 | 0.94 | S1PR3 (0.40) | MAPKAPK2MAPK14CXCR2TEAD4 | |
| SCHEMBL7785672 | 0.93 | S1PR3 (0.39) | MAPKAPK2MAPK14CXCR2TEAD4 | |
| Hydrochloric Acid SCHEMBL7801207 | 0.93 | S1PR3 (0.38) | MAPKAPK2MAPK14CXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | claimed |