SCHEMBL7785300

SCHEMBL7785300

O=C(O)c1ccc(N(Cl)S(=O)(=O)O)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.53
ALDH1A1 P00352 2/20 0.53
TSHR P16473 3/20 0.48
TP53 P04637 1/20 0.48
ALOX15 P16050 1/20 0.45
CA2 P00918 5/20 0.44
CA1 P00915 4/20 0.44
CA12 O43570 4/20 0.44
CA9 Q16790 4/20 0.44
CA14 Q9ULX7 3/20 0.44
CA3 P07451 2/20 0.44
CA6 P23280 2/20 0.44
CA5A P35218 2/20 0.44
CA7 P43166 2/20 0.44
CA5B Q9Y2D0 2/20 0.44
CYP2C19 P33261 1/20 0.44
SRD5A2 P31213 3/20 0.43
MEN1 O00255 1/20 0.42
NPC1 O15118 1/20 0.42
POLB P06746 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31006397 0.77 TSHR (0.46) KMT2AALDH1A1TSHRCA2CA1
SCHEMBL11842036 0.77 SMN1; SMN2 (0.41) KMT2AALDH1A1TSHRTP53ALOX15
Water SCHEMBL10524804 0.75 SMN1; SMN2 (0.39) KMT2AALDH1A1TSHRTP53ALOX15
Terephthalic Acid SCHEMBL17210199 0.75 TSHR (0.75) KMT2AALDH1A1TSHRTP53ALOX15
SCHEMBL2116518 0.73 MAPT (0.42) KMT2AALDH1A1TSHRTP53CA2
Terephthalic Acid SCHEMBL29007040 0.73 TSHR (0.71) KMT2AALDH1A1TSHRTP53ALOX15
Terephthalic Acid SCHEMBL28266394 0.73 TSHR (0.71) KMT2AALDH1A1TSHRTP53ALOX15
SCHEMBL12697477 0.72 TSHR (0.55) KMT2AALDH1A1TSHRTP53ALOX15
SCHEMBL10371035 0.71 TSHR (0.52) KMT2AALDH1A1TSHRTP53ALOX15
Terephthalic Acid SCHEMBL28813358 0.71 TSHR (0.67) KMT2AALDH1A1TSHRTP53ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0623119-B1 NOVEL 3-HALO-5-HALOMETHYL-2-OXAZOLIDINONES AND THEIR USE AS MICROBICIDES BUCKMAN LABOR INC (US) 2001-11-28 EP disclosed
EP-0827690-B1 Sulphur-containing quaternary ammonium ionene polymers and their use as microbicides BUCKMAN LABOR INC (US) 2000-09-27 EP disclosed
EP-0607420-B1 METHOD FOR THE DETOXIFICATION OF MUSTARD GAS, AND SULFUR-CONTAINING QUATERNARY AMMONIUM IONENE POLYMERS BUCKMAN LABOR INC (US) 1998-11-04 EP disclosed
EP-0827690-A2 Sulphur-containing quaternary ammonium ionene polymers and their use as microbicides BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) 1998-03-11 EP disclosed
US-5703131-A Method for the detoxification of mustard gas sulfur-containing quaternary ammonium ionene polymers and their use as microbicides BUCKMAN LABORATORIES INTERNATIONAL INC. (US) 1997-12-30 US disclosed
US-5401881-A Sulfur-containing quaternary ammonium ionene polymers and their use as microbicides BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) 1995-03-28 US disclosed
US-5387717-A Method for the detoxification of mustard gas, sulfur-containing quaternary ammonium ionene polymers and their use as microbicides BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) 1995-02-07 US disclosed
EP-0623119-A1 NOVEL 3-HALO-5-HALOMETHYL-2-OXAZOLIDINONES AND THEIR USE AS MICROBICIDES BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) 1994-11-09 EP disclosed
EP-0607420-A1 METHOD FOR THE DETOXIFICATION OF MUSTARD GAS, SULFUR-CONTAINING QUATERNARY AMMONIUM IONENE POLYMERS AND THEIR USE AS MICROBICIDES BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) 1994-07-27 EP disclosed
WO-1994004225-A2 METHOD FOR THE DETOXIFICATION OF MUSTARD GAS, SULFUR-CONTAINING QUATERNARY AMMONIUM IONENE POLYMERS AND THEIR USE AS MICROBICIDES BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) 1994-03-03 WO disclosed
WO-1993013081-A1 NOVEL 3-HALO-5-HALOMETHYL-2-OXAZOLIDINONES AND THEIR USE AS MICROBICIDES BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) 1993-07-08 WO disclosed
US-5162354-A For controlling growth of microorganisms in aqueous system or surface BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) 1992-11-10 US disclosed
US-4338331-A DIURETIC, SLLURETIC, HYPOTENSIVE FARMATIS S.P.A. (IT) 1982-07-06 US disclosed