Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HTR7 | P34969 | 2/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.48 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.46 |
| ▸ | TOP2A | P11388 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7792612 | 0.95 | KCNA3 (0.51) | MAPTCHRNA7KMT2AHTR7ADORA2A | |
| SCHEMBL7794682 | 0.94 | KCNA3 (0.50) | MAPTCHRNA7KMT2AKCNA3TOP2A | |
| SCHEMBL8517442 | 0.91 | KCNA3 (0.54) | MAPTCHRNA7KMT2AHTR7ADORA2A | |
| SCHEMBL7786287 | 0.88 | MAPT (0.71) | MAPTCHRNA7KMT2AADORA2AADORA1 | |
| SCHEMBL7792348 | 0.86 | MAPT (0.59) | MAPTCHRNA7KMT2AADORA2AADORA1 | |
| SCHEMBL8386455 | 0.86 | MAPT (0.56) | MAPTCHRNA7KMT2AADORA2AADORA1 | |
| SCHEMBL7792554 | 0.84 | MAPT (0.67) | MAPTCHRNA7KMT2AADORA2AADORA1 | |
| SCHEMBL7796349 | 0.84 | MAPT (0.67) | MAPTCHRNA7KMT2AADORA2AADORA1 | |
| SCHEMBL7795949 | 0.84 | MAPT (0.62) | MAPTCHRNA7KMT2AADORA2AADORA1 | |
| SCHEMBL9335025 | 0.83 | KMT2A (0.67) | MAPTCHRNA7KMT2AADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0906268-B1 | ALKYLOXYAMINO SUBSTITUTED FLUORENONES AND THEIR USE AS PROTEIN KINASE C INHIBITORS | AVENTIS PHARMA INC (US) | 2001-11-28 | — | — | EP | disclosed |
| US-6004959-A | HYPOTENSIVE, ANTITUMOR, ANTIINFLAMMATORY AND ANTIASTHMATIC AGENTS; ANGIOGENESIS AND ALVEOLAR MACROPHAGE ACTIVATION INHIBITORS | HOECHST MARION ROUSSEL, INC. (US) | 1999-12-21 | — | — | US | disclosed |