Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5986995 | 1.00 | TSHR (0.39) | TSHRSMN1; SMN2LMNAADRB2ADRB1 | |
| SCHEMBL5986993 | 0.98 | SMN1; SMN2 (0.40) | TSHRSMN1; SMN2LMNAADRB2ADRB1 | |
| SCHEMBL7601928 | 0.98 | SMN1; SMN2 (0.40) | TSHRSMN1; SMN2LMNAADRB2ADRB1 | |
| SCHEMBL7795103 | 0.98 | SMN1; SMN2 (0.40) | TSHRSMN1; SMN2LMNAADRB2ADRB1 | |
| SCHEMBL10650039 | 0.90 | SMN1; SMN2 (0.44) | TSHRSMN1; SMN2LMNAADRB2ADRB1 | |
| Acetic Acid SCHEMBL10786749 | 0.88 | SMN1; SMN2 (0.41) | SMN1; SMN2LMNAADRB2ADRB1ADRB3 | |
| SCHEMBL7601634 | 0.83 | PIK3CD (0.37) | TSHR | |
| SCHEMBL5987773 | 0.83 | PIK3CD (0.37) | TSHR | |
| SCHEMBL7606612 | 0.83 | PIK3CD (0.37) | TSHR | |
| SCHEMBL16667300 | 0.83 | SMN1; SMN2 (0.34) | TSHRSMN1; SMN2LMNAHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010150840-A1 | N-SUBSTITUTED-CYCLIC AMINO DERIVATIVE | 大日本住友製薬株式会社 (JP) | 2010-12-29 | — | — | WO | disclosed |