SCHEMBL778699

SCHEMBL778699

Cc1ccccc1C(=O)OS(=O)OC(=O)c1ccccc1C

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.47
RAB9A P51151 2/20 0.47
MEN1 O00255 4/20 0.45
KMT2A Q03164 4/20 0.45
ESR1 P03372 1/20 0.45
ESR2 Q92731 1/20 0.45
LMNA P02545 1/20 0.44
MAPT P10636 1/20 0.44
TSHR P16473 1/20 0.44
PLK1 P53350 1/20 0.43
PLK2 Q9NYY3 1/20 0.43
CASP3 P42574 1/20 0.43
SENP8 Q96LD8 1/20 0.43
SENP7 Q9BQF6 1/20 0.43
SENP6 Q9GZR1 1/20 0.43
HPGD P15428 1/20 0.43
ADRB2 P07550 2/20 0.42
ADRB1 P08588 2/20 0.42
ADRB3 P13945 2/20 0.42
ERCC5 P28715 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL778215 0.91 NPC1 (0.44) NPC1RAB9AMEN1KMT2AESR1
SCHEMBL776602 0.86 NPC1 (0.44) NPC1RAB9AMEN1KMT2AESR1
SCHEMBL780059 0.86 TSHR (0.49) NPC1RAB9AMEN1KMT2AESR1
SCHEMBL29436920 0.79 NPC1 (0.53) NPC1RAB9AMEN1KMT2AESR1
SCHEMBL127127 0.79 NPC1 (0.53) NPC1RAB9AMEN1KMT2AESR1
SCHEMBL777261 0.79 NPC1 (0.53) NPC1RAB9AMEN1KMT2AESR1
SCHEMBL29702037 0.77 TSHR (0.63) NPC1RAB9AKMT2ALMNAMAPT
SCHEMBL101601 0.77 TSHR (0.63) NPC1RAB9AKMT2ALMNAMAPT
SCHEMBL248052 0.77 KMT2A (0.53) NPC1RAB9AMEN1KMT2AESR1
SCHEMBL4303133 0.75 NPC1 (0.50) NPC1RAB9AMEN1KMT2AESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109912503-B Synthetic method of 2, 3-diacyl quinoline compound 江南大学 2022-04-08 CN disclosed
US-9343777-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2016-05-17 US disclosed
US-9252457-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2016-02-02 US disclosed
US-20120177988-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-07-12 US disclosed
US-20120070731-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-03-22 US disclosed