SCHEMBL7787030

SCHEMBL7787030

CN1c2ccccc2C(C(=O)Oc2cccc3ccccc23)c2ccccc21

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.54
MEN1 O00255 1/20 0.54
RAB9A P51151 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
FABP3 P05413 7/20 0.51
FABP7 O15540 6/20 0.51
FABP5 Q01469 4/20 0.51
ALDH1A1 P00352 3/20 0.48
HSD17B10 Q99714 3/20 0.48
PGR P06401 1/20 0.48
GAA P10253 1/20 0.48
PTGS1 P23219 1/20 0.48
MAPK1 P28482 1/20 0.48
HDAC4 P56524 1/20 0.48
HDAC7 Q8WUI4 1/20 0.48
HDAC5 Q9UQL6 1/20 0.48
BCHE P06276 1/20 0.47
SLC6A3 Q01959 1/20 0.47
KDM4E B2RXH2 3/20 0.42
HPGD P15428 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13005786 0.93 HDAC4 (0.51) KMT2AMEN1RAB9AL3MBTL1FABP3
SCHEMBL7042511 0.88 HDAC4 (0.42) KMT2AMEN1RAB9AL3MBTL1FABP3
SCHEMBL7797024 0.82 HDAC4 (0.49) KMT2AMEN1L3MBTL1FABP3FABP7
SCHEMBL7795339 0.82 HDAC4 (0.51) KMT2AMEN1L3MBTL1FABP3FABP7
SCHEMBL8741687 0.82 HDAC4 (0.51) KMT2AMEN1L3MBTL1FABP3FABP7
SCHEMBL8741624 0.81 HDAC4 (0.50) KMT2AMEN1RAB9AL3MBTL1ALDH1A1
SCHEMBL8741803 0.81 HDAC4 (0.50) KMT2AMEN1L3MBTL1FABP3FABP7
SCHEMBL8741715 0.80 HDAC4 (0.47) KMT2AMEN1L3MBTL1ALDH1A1GAA
SCHEMBL38662006 0.80 HDAC4 (0.49) KMT2AMEN1L3MBTL1FABP3FABP7
SCHEMBL7787035 0.80 HDAC4 (0.49) KMT2AMEN1L3MBTL1FABP3FABP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0750748-B1 NOVEL ARYL N-ALKYLACRIDANCARBOXYLATE DERIVATIVES USEFUL FOR CHEMILUMINESCENT DETECTION LUMIGEN INC (US) 2001-12-05 EP disclosed
US-5750698-A USEFUL IN DETECTING BOTH PEROXIDASE AND PEROXIDE LUMIGEN, INC. (US) 1998-05-12 US disclosed
US-5593845-A BY REACTION WITH PEROXIDES AND PEROXIDASE; DETECTION OF HAPTENS, PROTEINS, ANTIBODIES IN ENZYME IMMUNOASSAY LUMIGEN, INC. (US) 1997-01-14 US disclosed
WO-1995023971-A1 NOVEL ARYL N-ALKYLACRIDANCARBOXYLATE DERIVATIVES USEFUL FOR CHEMILUMINESCENT DETECTION LUMIGEN, INC. (US) 1995-09-08 WO disclosed