Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 17/20 | 0.34 |
| ▸ | CNR2 | P34972 | 15/20 | 0.34 |
| ▸ | GPR18 | Q14330 | 3/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL224924 | 0.92 | CNR1 (0.38) | CNR1CNR2GPR18GPR55NPC1 | |
| SCHEMBL10484223 | 0.91 | CNR2 (0.37) | CNR1CNR2GPR18GPR55NPC1 | |
| SCHEMBL5648044 | 0.90 | CNR2 (0.36) | CNR1CNR2GPR18GPR55NPC1 | |
| SCHEMBL5647618 | 0.90 | CNR2 (0.37) | CNR1CNR2GPR18GPR55NPC1 | |
| SCHEMBL5648165 | 0.90 | CNR2 (0.37) | CNR1CNR2GPR18GPR55NPC1 | |
| SCHEMBL5834592 | 0.90 | CNR1 (0.34) | CNR1CNR2GPR18GPR55NPC1 | |
| SCHEMBL769153 | 0.90 | CNR1 (0.36) | CNR1CNR2GPR18GPR55NPC1 | |
| SCHEMBL5834169 | 0.90 | CNR1 (0.37) | CNR1CNR2GPR18GPR55NPC1 | |
| SCHEMBL10384689 | 0.89 | CNR2 (0.39) | CNR1CNR2GPR18GPR55NPC1 | |
| SCHEMBL225356 | 0.89 | CNR2 (0.35) | CNR1CNR2GPR18GPR55NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144391-A1 | ONE-POT PROCESS FOR THE PREPARATION OF 5-SULFONYL-SUBSTITUTED BENZOTRIAZOLES | Ciba SC Holding AG (CH) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000043376-A1 | ONE-POT PROCESS FOR THE PREPARATION OF 5-SULFONYL-SUBSTITUTED BENZOTRIAZOLES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-07-27 | — | — | WO | disclosed |
| US-6040455-A | REACTING A HALOBENZOTRIAZOLE COMPOUND WITH ALIPHATIC, PHENYLALKYL OR ARYL MERCAPTAN COMPOUND TO FORM 5-THIO SUBSTITUTED BENZOTRIAZOLE, OXIDIZING WITH HYDROGEN PEROXIDE TO FOR 5-SULFONE SUBSTITUED BENZOTRIAZOLE COMPOUND | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-03-21 | — | — | US | disclosed |