Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.31 |
| ▸ | FDPS | P14324 | 8/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7787404 | 1.00 | TSHR (0.32) | TSHRTHRBGGPS1FDPS | |
| SCHEMBL7098197 | 0.98 | TSHR (0.31) | TSHR | |
| SCHEMBL7098199 | 0.98 | TSHR (0.31) | TSHR | |
| SCHEMBL7781967 | 0.96 | TSHR (0.35) | TSHRTHRBGGPS1FDPS | |
| SCHEMBL7095037 | 0.96 | TSHR (0.35) | TSHRTHRBGGPS1FDPS | |
| SCHEMBL7781965 | 0.96 | TSHR (0.35) | TSHRTHRBGGPS1FDPS | |
| SCHEMBL7095039 | 0.96 | TSHR (0.35) | TSHRTHRBGGPS1FDPS | |
| SCHEMBL3061988 | 0.96 | TSHR (0.35) | TSHRTHRBGGPS1FDPS | |
| SCHEMBL7786673 | 0.94 | — | — | |
| SCHEMBL11763639 | 0.94 | TSHR (0.33) | TSHRTHRBGGPS1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0847383-B1 | MULTI-COMPONENT LIQUID AZODINITRILE MIXTURES | DU PONT (US) | 2001-11-07 | — | — | EP | claimed |
| US-4061590-A | Catalyst composition of an azo nitrile mixture in an organic solvent | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-12-06 | — | — | US | claimed |
| US-3987025-A | POLYMERIZATION INITIATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-10-19 | — | — | US | claimed |
| EP-0847383-B1 | MULTI-COMPONENT LIQUID AZODINITRILE MIXTURES | DU PONT (US) | 2001-11-07 | — | — | EP | disclosed |
| US-5760192-A | FREE RADICAL, POLYMERIZATION CATALYSTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-06-02 | — | — | US | disclosed |
| US-4061590-A | Catalyst composition of an azo nitrile mixture in an organic solvent | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-12-06 | — | — | US | disclosed |
| US-3987025-A | POLYMERIZATION INITIATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-10-19 | — | — | US | disclosed |
| US-3987025-A | POLYMERIZATION INITIATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-10-19 | — | — | US | disclosed |