Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 7/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 4/20 | 0.31 |
| ▸ | ACACA | Q13085 | 2/20 | 0.31 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.31 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7780562 | 0.93 | POLB (0.39) | MAPKAPK2POLBLMNAMAPK14MAPT | |
| SCHEMBL7787853 | 0.89 | KMT2A (0.38) | MAPKAPK2POLBLMNAMAPK14TP53 | |
| SCHEMBL7784926 | 0.89 | KMT2A (0.38) | MAPKAPK2POLBLMNAMAPK14TP53 | |
| SCHEMBL7780520 | 0.89 | MAPKAPK2 (0.38) | MAPKAPK2POLBMAPK14 | |
| SCHEMBL7785255 | 0.88 | MAPKAPK2 (0.35) | MAPKAPK2POLBMAPK14 | |
| SCHEMBL7780422 | 0.88 | MAPKAPK2 (0.41) | MAPKAPK2MAPK14 | |
| SCHEMBL7785641 | 0.87 | MAPKAPK2 (0.36) | MAPKAPK2POLBMAPK14 | |
| SCHEMBL7780413 | 0.86 | MAPKAPK2 (0.35) | MAPKAPK2POLBMAPK14 | |
| SCHEMBL7785106 | 0.86 | MAPKAPK2 (0.35) | MAPKAPK2POLBMAPK14 | |
| Hydrochloric Acid SCHEMBL7805381 | 0.86 | CXCL12 (0.36) | MAPKAPK2CXCL12LMNAKLKB1ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |