Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 8/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 8/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | NMUR2 | Q9GZQ4 | 2/20 | 0.34 |
| ▸ | NMUR1 | Q9HB89 | 2/20 | 0.34 |
| ▸ | TRHR | P34981 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7787536 | 1.00 | HDAC3 (0.40) | HDAC3HDAC11HDAC6HDAC1HDAC2 | |
| SCHEMBL7788533 | 0.94 | HDAC3 (0.42) | HDAC3HDAC11HDAC6HDAC1HDAC2 | |
| SCHEMBL7788528 | 0.94 | HDAC3 (0.42) | HDAC3HDAC11HDAC6HDAC1HDAC2 | |
| SCHEMBL29727699 | 0.88 | OPRL1 (0.43) | — | |
| Nonathymulin SCHEMBL2109423 | 0.84 | OPRL1 (0.42) | — | |
| Nonathymulin SCHEMBL29727660 | 0.84 | OPRL1 (0.42) | — | |
| SCHEMBL10741543 | 0.83 | SMN1; SMN2 (0.35) | HDAC3HDAC11HDAC6HDAC1HDAC2 | |
| SCHEMBL30844021 | 0.82 | HDAC3 (0.47) | HDAC3HDAC11HDAC6HDAC1HDAC2 | |
| SCHEMBL10341274 | 0.80 | HDAC3 (0.42) | HDAC3HDAC11HDAC6HDAC1HDAC2 | |
| SCHEMBL10744274 | 0.80 | OPRL1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1150689-A1 | CHEMICAL COMPOUNDS | NORSK HYDRO ASA (NO) | 2001-11-07 | — | — | EP | disclosed |
| EP-1150690-A1 | CHEMICAL COMPOUNDS | NORSK HYDRO ASA (NO) | 2001-11-07 | — | — | EP | disclosed |
| WO-2000048610-A1 | CHEMICAL COMPOUNDS | NORSK HYDRO ASA (NO) | 2000-08-24 | — | — | WO | disclosed |
| WO-2000048609-A1 | CHEMICAL COMPOUNDS | NORSK HYDRO ASA (NO) | 2000-08-24 | — | — | WO | disclosed |