Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 9/20 | 0.45 |
| ▸ | ESR1 | P03372 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1905793 | 1.00 | ESR2 (0.45) | ESR2ESR1MEN1KMT2AHSD17B10 | |
| SCHEMBL7789804 | 0.91 | ESR2 (0.41) | ESR2ESR1MEN1KMT2AHSD17B10 | |
| SCHEMBL7782046 | 0.91 | ESR2 (0.41) | ESR2ESR1MEN1KMT2AHSD17B10 | |
| SCHEMBL7789832 | 0.91 | ESR2 (0.38) | ESR2ESR1 | |
| SCHEMBL7786899 | 0.86 | ESR2 (0.40) | ESR2ESR1MEN1KMT2AHSD17B10 | |
| SCHEMBL1888940 | 0.86 | ESR2 (0.42) | ESR2ESR1GRM2 | |
| SCHEMBL7782050 | 0.86 | ESR2 (0.42) | ESR2ESR1GRM2 | |
| SCHEMBL1892183 | 0.85 | ESR2 (0.43) | ESR2ESR1GRM2 | |
| SCHEMBL7789806 | 0.85 | ESR2 (0.43) | ESR2ESR1GRM2 | |
| SCHEMBL1888520 | 0.84 | ESR2 (0.41) | ESR2ESR1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6251898-B1 | Medical use of fluorenone derivatives for treating and preventing brain and spinal injury | QUESTCOR PHARMACEUTICALS, INC. | 2001-06-26 | — | — | US | disclosed |