Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 2/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 13/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7787476 | 0.94 | MAPKAPK2 (0.39) | MAPKAPK2MAPK14TDO2 | |
| SCHEMBL7788883 | 0.94 | S1PR3 (0.35) | S1PR3MAPKAPK2MAPK14POLBTDO2 | |
| SCHEMBL7785012 | 0.94 | S1PR3 (0.35) | S1PR3MAPKAPK2MAPK14POLBTDO2 | |
| SCHEMBL7787795 | 0.94 | MAPKAPK2 (0.36) | S1PR3MAPKAPK2MAPK14POLBMEN1 | |
| SCHEMBL7787734 | 0.94 | MAPKAPK2 (0.36) | S1PR3MAPKAPK2MAPK14POLBMEN1 | |
| SCHEMBL7787581 | 0.93 | S1PR3 (0.37) | S1PR3MAPKAPK2MAPK14POLBMEN1 | |
| SCHEMBL7785097 | 0.93 | MAPKAPK2 (0.39) | S1PR3MAPKAPK2MAPK14POLBTDO2 | |
| SCHEMBL7785124 | 0.93 | S1PR3 (0.37) | S1PR3MAPKAPK2MAPK14POLBMEN1 | |
| SCHEMBL7785270 | 0.91 | KMT2A (0.38) | MAPKAPK2MAPK14POLBMEN1KMT2A | |
| SCHEMBL7780305 | 0.91 | KMT2A (0.38) | MAPKAPK2MAPK14POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |