Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL9 | O00512 | 1/20 | 0.57 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MGLL | Q99685 | 2/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28323255 | 0.86 | BCL9 (0.51) | BCL9CTNNB1GAAMGLLHTR2A | |
| SCHEMBL11221524 | 0.85 | BCL9 (0.51) | BCL9CTNNB1GAAMGLLHTR2A | |
| SCHEMBL11221520 | 0.85 | BCL9 (0.51) | BCL9CTNNB1GAAMGLLHTR2A | |
| SCHEMBL9068344 | 0.85 | BCL9 (0.50) | BCL9CTNNB1GAAMGLLHTR2A | |
| SCHEMBL13629555 | 0.84 | BCL9 (0.60) | BCL9CTNNB1GAAMGLLHTR2A | |
| SCHEMBL6707349 | 0.84 | BCL9 (0.49) | BCL9CTNNB1GAAMGLLHTR2A | |
| SCHEMBL11796565 | 0.84 | BCL9 (0.49) | BCL9CTNNB1GAAMGLLHTR2A | |
| SCHEMBL10335399 | 0.84 | BCL9 (0.49) | BCL9CTNNB1GAAMGLLHTR2A | |
| SCHEMBL10024490 | 0.83 | BCL9 (0.59) | BCL9CTNNB1GAAMGLLHTR2A | |
| SCHEMBL515913 | 0.83 | GAA (0.57) | BCL9CTNNB1GAAMGLLHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1147076-A1 | ACRYLAMIDE DERIVATIVES AND POLYMERS CONTAINING SAID DERIVATIVES | Amersham Pharmacia Biotech K.K. (JP) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000043355-A1 | ACRYLAMIDE DERIVATIVES AND POLYMERS CONTAINING SAID DERIVATIVES | AMERSHAM PHARMACIA BIOTECH K.K. (JP) | 2000-07-27 | — | — | WO | disclosed |