Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PTPRB | P23467 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11851533 | 0.86 | TSHR (0.45) | TSHRLMNAALDH1A1RECQLKMT2A | |
| SCHEMBL14809987 | 0.85 | TSHR (0.52) | TSHRLMNAALDH1A1RECQLKMT2A | |
| SCHEMBL28738660 | 0.85 | TSHR (0.52) | TSHRLMNAALDH1A1RECQLKMT2A | |
| SCHEMBL14891456 | 0.85 | TSHR (0.52) | TSHRLMNAALDH1A1RECQLKMT2A | |
| SCHEMBL28887136 | 0.83 | TSHR (0.54) | TSHRLMNAALDH1A1RECQLKMT2A | |
| SCHEMBL23199993 | 0.81 | MAPT (0.44) | TSHRLMNAKMT2AL3MBTL1CYP4F2 | |
| SCHEMBL11048521 | 0.81 | MAPT (0.44) | TSHRLMNAKMT2AL3MBTL1CYP4F2 | |
| SCHEMBL5797151 | 0.81 | MAPT (0.44) | TSHRLMNAKMT2AL3MBTL1CYP4F2 | |
| SCHEMBL21015916 | 0.81 | TSHR (0.56) | TSHRLMNAALDH1A1RECQLKMT2A | |
| SCHEMBL17807141 | 0.81 | POLB (0.47) | TSHRLMNAALDH1A1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0638392-B1 | Coated abrasives comprising a moisture cured polyurethane hot melt make coating | MINNESOTA MINING & MFG (US) | 2001-10-31 | — | — | EP | disclosed |
| US-5595578-A | BACKING AND SUBSTRATE FOR ABRASIVES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-01-21 | — | — | US | disclosed |
| EP-0638392-A1 | Coated abrasives utilizing a moisture curable polyurethane hot melt make coating | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-02-15 | — | — | EP | disclosed |