⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7788279 | 1.00 | — | — | |
| SCHEMBL7788295 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL7796306 | 0.71 | — | — | |
| SCHEMBL14216992 | 0.67 | — | — | |
| SCHEMBL731695 | 0.67 | — | — | |
| SCHEMBL21606266 | 0.67 | SMN1; SMN2 (0.39) | — | |
| SCHEMBL13703241 | 0.65 | — | — | |
| SCHEMBL26305272 | 0.65 | — | — | |
| SCHEMBL22693984 | 0.64 | — | — | |
| SCHEMBL29777483 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0870763-B1 | Condensed piperidine derivatives used as a nitrogen monoxide synthase inhibitors | ONO PHARMACEUTICAL CO (JP) | 2001-12-12 | — | — | EP | disclosed |
| US-6228866-B1 | ADMINISTERING NITRIC OXIDE SYNTHASE INHIBITOR TO TREAT CANCER AND NERVOUS SYSTEM, BRAIN, KIDNEY, RESPIRATORY SYSTEM, AUTOIMMUNES, SKIN AND MUSCULAR DISORDERS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-05-08 | — | — | US | disclosed |
| US-6110930-A | NITRIC OXIDE SYNTHASE INHIBITOR | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-08-29 | — | — | US | disclosed |
| EP-0870763-A1 | Condensed piperidine derivatives used as a nitrogen monoxide synthase inhibitors | ONO PHARMACEUTICAL CO., LTD. (JP) | 1998-10-14 | — | — | EP | disclosed |