SCHEMBL7788700

SCHEMBL7788700

CCCCC(CC)COC(=O)C(=O)OCl

nearest known ligand 0.60

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.60
TSHR P16473 3/20 0.60
TDP1 Q9NUW8 3/20 0.60
ATM Q13315 1/20 0.60
ALDH1A1 P00352 7/20 0.53
CA2 P00918 4/20 0.53
RECQL P46063 1/20 0.50
LMNA P02545 3/20 0.48
MAPK1 P28482 3/20 0.48
L3MBTL1 Q9Y468 1/20 0.47
HSD17B10 Q99714 1/20 0.47
PRSS1 P07477 1/20 0.47
PRSS2 P07478 1/20 0.47
PRSS3 P35030 1/20 0.47
MMP9 P14780 1/20 0.41
MMP8 P22894 1/20 0.41
MMP14 P50281 1/20 0.41
CA1 P00915 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL257295 0.91 CYP3A4 (0.70) CYP3A4TSHRTDP1ATMALDH1A1
SCHEMBL27764095 0.86 CYP3A4 (0.64) CYP3A4TSHRTDP1ATMALDH1A1
SCHEMBL7788704 0.84 CYP3A4 (0.62) CYP3A4TSHRTDP1ATMALDH1A1
SCHEMBL15632856 0.84 CYP3A4 (0.62) CYP3A4TSHRTDP1ATMALDH1A1
SCHEMBL16772 0.83 TSHR (0.61) CYP3A4TSHRTDP1ATMALDH1A1
SCHEMBL859732 0.83 CYP3A4 (0.60) CYP3A4TSHRTDP1ATMALDH1A1
SCHEMBL8485577 0.83 CYP3A4 (0.60) CYP3A4TSHRTDP1ATMALDH1A1
SCHEMBL1269088 0.83 TSHR (0.61) CYP3A4TSHRTDP1ATMALDH1A1
SCHEMBL5487010 0.82 CYP3A4 (0.64) CYP3A4TSHRTDP1ATMALDH1A1
SCHEMBL146937 0.82 CYP3A4 (0.68) CYP3A4TSHRTDP1ATMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0850928-B1 Novel peroxyoxalates derived from hydroxy-hydroperoxides ATOFINA CHEM INC (US) 2001-10-31 EP disclosed
EP-0850929-B1 Novel bis(mono- and diperoxy-oxalates) derived from dihydroperoxides and alkyl and alkylperoxy halooxalates ATOFINA CHEM INC (US) 2001-06-27 EP disclosed
US-5981787-A INITIATORS FOR POLYMERIZING ETHYLENICALLY UNSATURATED MONOMERS AND FOR CURING OF UNSATURATED POLYESTER RESINS ELF ATOCHEM NORTH AMERICA, INC. (US) 1999-11-09 US disclosed
US-5837782-A POLYMERIZATION CATALYST ELF ATOCHEM NORTH AMERICA, INC. (US) 1998-11-17 US disclosed
CN-1187487-A Novel peroxyoxalates derived from hydroxy-hydroperoxides ATOCHEM NORTH AMERICA ELF (US) 1998-07-15 CN disclosed
CN-1186803-A Novel bis (mono-and diperoxyoxalates) derived from dihydroperoxides and alkyl and alkylperoxy halooxalates ATOCHEM NORTH AMERICA ELF (US) 1998-07-08 CN disclosed
EP-0850928-A1 Novel peroxyoxalates derived from hydroxy-hydroperoxides ELF ATOCHEM NORTH AMERICA, INC. (US) 1998-07-01 EP disclosed
EP-0850929-A1 Novel bis(mono- and diperoxy-oxalates) derived from dihydroperoxides and alkyl and alkylperoxy halooxalates ELF ATOCHEM NORTH AMERICA, INC. (US) 1998-07-01 EP disclosed