SCHEMBL7788916

SCHEMBL7788916

CCOC(=O)NC1CCC(NC(=O)OCC)CC1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMYD3 Q9H7B4 1/20 0.47
EPHX1 P07099 3/20 0.47
NFKB1 P19838 1/20 0.47
NFKB2 Q00653 1/20 0.47
RELA Q04206 1/20 0.47
DRD2 P14416 1/20 0.47
HSD11B1 P28845 1/20 0.46
GAA P10253 3/20 0.44
ALDH1A1 P00352 1/20 0.44
MGAM O43451 1/20 0.42
SI P14410 1/20 0.42
MGAM2 Q2M2H8 1/20 0.42
MAPK1 P28482 1/20 0.41
HTT P42858 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
TSHR P16473 1/20 0.41
KDM4E B2RXH2 1/20 0.41
LMNA P02545 1/20 0.41
THRB P10828 1/20 0.41
ATM Q13315 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18380884 1.00 SMYD3 (0.47) SMYD3EPHX1NFKB1NFKB2RELA
SCHEMBL7470486 1.00
Hydrochloric Acid SCHEMBL3971132 0.98 SMYD3 (0.46) SMYD3EPHX1NFKB1NFKB2RELA
SCHEMBL12513735 0.92 EPHX1 (0.46) SMYD3EPHX1NFKB1NFKB2RELA
SCHEMBL5949999 0.92 EPHX1 (0.48) SMYD3EPHX1NFKB1NFKB2RELA
SCHEMBL6483370 0.92 EPHX2 (0.52) SMYD3EPHX1NFKB1NFKB2RELA
SCHEMBL22722037 0.92 EPHX1 (0.46) SMYD3EPHX1NFKB1NFKB2RELA
SCHEMBL15906231 0.92 EPHX1 (0.48) SMYD3EPHX1NFKB1NFKB2RELA
SCHEMBL8396643 0.91 EPHX1 (0.53) EPHX1NFKB1NFKB2RELAHSD11B1
SCHEMBL1053459 0.91 EPHX1 (0.57) EPHX1GAAALDH1A1HTTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250188021-A1 PREPARATION METHOD FOR ALICYCLIC CARBAMATE AND USE THEREOF INSTITUTE OF PROCESS ENGINEERING, CHINESE ACADEMY OF SCIENCES (CN) 2025-06-12 US disclosed
WO-2017009357-A1 POLYAMIDE COMPOSITIONS HAVING IMPROVED OPTICAL PROPERTIES BASF SE (DE) 2017-01-19 WO disclosed
US-9000219-B2 Method for treatment of isocyanate residue, and method for treatment of carbonate MITSUI CHEMICALS, INC. (JP) 2015-04-07 US disclosed
US-20120271067-A1 METHOD FOR TREATMENT OF ISOCYANATE RESIDUE, AND METHOD FOR TREATMENT OF CARBONATE MITSUI CHEMICALS, INC. 2012-10-25 US disclosed
EP-0795544-B1 Process for the thermal decomposition of carbamic esters BAYER AG (DE) 2001-10-31 EP disclosed
EP-0795543-B1 Use of high boiling solvents or solvent mixtures as heat exchange medium in the thermal decomposition of carbamic esters BAYER AG (DE) 2001-10-31 EP disclosed
US-5883291-A Heat exchange media for the thermal cracking of carbamic acid esters BAYER AKTIENGESELLSCHAFT (DE) 1999-03-16 US disclosed
US-5731458-A Process for thermally cracking carbamic acid esters BAYER AKTIENGESELLSCHAFT (DE) 1998-03-24 US disclosed
EP-0795544-A1 Process for the thermal decomposition of carbamic esters BAYER AG (DE) 1997-09-17 EP disclosed
EP-0795543-A1 Use of high boiling solvents or solvent mixtures as heat exchange medium in the thermal decomposition of carbamic esters BAYER AG (DE) 1997-09-17 EP disclosed
EP-0542106-A2 Process for the preparation of polyisocyanates BAYER AG (DE) 1993-05-19 EP disclosed
US-5043471-A Process for the preparation of polyisocyanates BAYER AKTIENGESELLSCHAFT (DE) 1991-08-27 US disclosed
EP-0396977-A2 Process for the preparation of polyisocyanates BAYER AG (DE) 1990-11-14 EP disclosed
EP-0396976-A2 Process for the preparation of polyisocyanates BAYER AG (DE) 1990-11-14 EP disclosed
US-4692550-A Continuous process for thermal splitting of carbamic acid esters BAYER AKTIENGESELLSCHAFT (DE) 1987-09-08 US disclosed
EP-0092738-B1 PROCESS FOR THE CONTINUOUS THERMAL DECOMPOSITION OF CARBAMIC-ACID ESTERS BAYER AG (DE) 1985-07-24 EP disclosed
EP-0061013-B1 PROCESS FOR THE PREPARATION OF POLYISOCYANATES BAYER AG (DE) 1984-06-27 EP disclosed
EP-0092738-A1 Process for the continuous thermal decomposition of carbamic-acid esters BAYER AG (DE) 1983-11-02 EP disclosed
US-4388246-A THERMAL SPLITTING OF CARBAMATES BAYER AKTIENGESELLSCHAFT (DE) 1983-06-14 US disclosed
EP-0061013-A1 Process for the preparation of polyisocyanates BAYER AG (DE) 1982-09-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250188021-A1 PREPARATION METHOD FOR ALICYCLIC CARBAMATE AND USE THEREOF PAICS, CPS1, JMJD6 SMYD3 557/4885EPHX1 3941/4885NFKB1 3820/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.