SCHEMBL7789040

SCHEMBL7789040

COc1cc(F)c(/C=N/N=C/c2ccc(C)cc2)c(F)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.53
RAB9A P51151 2/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
ALDH1A1 P00352 1/20 0.46
CHRM5 P08912 1/20 0.44
RELA Q04206 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
RRM1 P23921 2/20 0.41
GRIN2D O15399 4/20 0.41
GRIN3B O60391 4/20 0.41
GRIN1 Q05586 4/20 0.41
GRIN2A Q12879 4/20 0.41
GRIN2B Q13224 4/20 0.41
GRIN2C Q14957 4/20 0.41
GRIN3A Q8TCU5 4/20 0.41
NQO2 P16083 1/20 0.39
CYP1A2 P05177 2/20 0.39
CYP1A1 P04798 1/20 0.39
CYP1B1 Q16678 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7789042 1.00 NPC1 (0.53) NPC1RAB9ASMN1; SMN2ALDH1A1CHRM5
SCHEMBL7791876 0.90 GRIN2D (0.50) ALDH1A1CHRM5RELARRM1GRIN2D
SCHEMBL7791872 0.90 GRIN2D (0.50) ALDH1A1CHRM5RELARRM1GRIN2D
SCHEMBL7788406 0.89 NQO2 (0.51) NPC1CHRM5KMT2ARRM1GRIN2D
SCHEMBL7788411 0.89 NQO2 (0.51) NPC1CHRM5KMT2ARRM1GRIN2D
SCHEMBL7791889 0.88 GRIN2D (0.47) NPC1RAB9ASMN1; SMN2ALDH1A1CHRM5
SCHEMBL7791884 0.88 GRIN2D (0.47) NPC1RAB9ASMN1; SMN2ALDH1A1CHRM5
SCHEMBL7793636 0.86 CHRM5 (0.42) CHRM5RRM1GRIN2DGRIN3BGRIN1
SCHEMBL7793635 0.86 CHRM5 (0.42) CHRM5RRM1GRIN2DGRIN3BGRIN1
SCHEMBL7793268 0.85 NPC1 (0.63) NPC1RAB9ASMN1; SMN2ALDH1A1CHRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0825176-B1 Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same DAINIPPON INK & CHEMICALS (JP) 2001-11-14 EP disclosed
US-6010642-A LIGHT SCATTERING LIQUID CRYSTAL DISPLAY DAINIPPON INK AND CHEMICALS, INC. (JP) 2000-01-04 US disclosed
EP-0825176-A1 Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same DAINIPPON INK AND CHEMICALS, INC. (JP) 1998-02-25 EP disclosed