Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CCR2 | P41597 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | UBE2M | P61081 | 1/20 | 0.41 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12883063 | 0.76 | TSHR (0.55) | MAPTSMN1; SMN2NPSR1TSHRSLC6A3 | |
| SCHEMBL5950293 | 0.71 | MAPT (0.63) | MAPTEPHX2SMN1; SMN2NPSR1TSHR | |
| SCHEMBL13375569 | 0.69 | CCR1 (0.70) | MAPTEPHX2SMN1; SMN2NPSR1TSHR | |
| SCHEMBL13375442 | 0.68 | CCR1 (0.80) | MAPTEPHX2SMN1; SMN2TSHRLMNA | |
| SCHEMBL13375973 | 0.68 | CCR1 (0.80) | MAPTEPHX2SMN1; SMN2TSHRLMNA | |
| SCHEMBL7797507 | 0.68 | HDAC6 (0.53) | MAPTEPHX2SMN1; SMN2NPSR1SLC6A3 | |
| SCHEMBL7795783 | 0.68 | HDAC6 (0.53) | MAPTEPHX2SMN1; SMN2NPSR1SLC6A3 | |
| SCHEMBL13375445 | 0.67 | CCR1 (0.79) | MAPTSMN1; SMN2NPSR1TSHRSLC6A3 | |
| SCHEMBL13376006 | 0.67 | CCR1 (0.79) | MAPTSMN1; SMN2NPSR1TSHRSLC6A3 | |
| SCHEMBL13374943 | 0.67 | CCR1 (0.79) | MAPTEPHX2SMN1; SMN2TSHRSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010151317-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2010-12-29 | — | — | WO | disclosed |