Oxirane

Oxirane

SCHEMBL7789725

C1CO1.C1COC(C2CO2)C1.O=C1CCCCO1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.53
CA9 Q16790 1/20 0.53
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
TP53 P04637 1/20 0.32
TSHR P16473 1/20 0.32
CYP2D6 P10635 1/20 0.32
FKBP4 Q02790 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8749849 0.80 CA1 (0.53) CA1CA9ALDH1A1LMNATP53
Oxirane SCHEMBL9486361 0.75 CA1 (0.84) CA1CA9ALDH1A1LMNATP53
Dioxane SCHEMBL28130980 0.73 CA1 (0.80) CA1CA9ALDH1A1LMNATP53
SCHEMBL2175853 0.73
SCHEMBL23530417 0.73 CA1 (0.58) CA1CA9ALDH1A1LMNATP53
SCHEMBL23530418 0.73 CA1 (0.58) CA1CA9ALDH1A1LMNATP53
SCHEMBL18685786 0.73
SCHEMBL19650557 0.73 CA1 (1.00) CA1CA9ALDH1A1LMNATP53
SCHEMBL14584221 0.73 CA1 (0.64) CA1CA9ALDH1A1LMNATP53
SCHEMBL189733 0.73 CA1 (1.00) CA1CA9ALDH1A1LMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0784229-B1 Photographic Emulsions EASTMAN KODAK CO (US) 2001-10-24 EP disclosed
US-5773207-A SILVER HALIDE EMULSIONS AND TETRAHYDROFURAN-ETHYLENE OXIDE COPOLYMERS IMATION CORP. (US) 1998-06-30 US disclosed
EP-0784229-A1 Photographic Emulsions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-07-16 EP disclosed