Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL775435 | 0.96 | S1PR2 (0.47) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL3451340 | 0.96 | S1PR2 (0.47) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL6262669 | 0.96 | S1PR2 (0.47) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL6259967 | 0.96 | S1PR2 (0.47) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL9807769 | 0.92 | HTT (0.46) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL17883707 | 0.92 | HTT (0.46) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL9464121 | 0.91 | HTT (0.47) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL10168299 | 0.91 | HTT (0.47) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL11231054 | 0.91 | S1PR2 (0.50) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL11230762 | 0.91 | S1PR2 (0.50) | HTTMEN1THRBKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0902780-B1 | QUATERNARY CYTOFECTINS | VICAL INC (US) | 2001-10-31 | — | — | EP | disclosed |
| US-5994317-A | DRUG DELIVERY; INSERTION MATERIAL INTO CELL | VICAL INCORPORATED (US) | 1999-11-30 | — | — | US | disclosed |