Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | HMGB1 | P09429 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GGT1 | P19440 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5176423 | 0.88 | KDM4E (0.65) | KDM4EHSD17B10ALDH1A1HPGDMAPK1 | |
| SCHEMBL16719153 | 0.88 | KDM4E (0.65) | KDM4EHSD17B10ALDH1A1HPGDMAPK1 | |
| SCHEMBL15656116 | 0.85 | KDM4E (0.61) | KDM4EHSD17B10ALDH1A1HPGDMAPK1 | |
| SCHEMBL8667165 | 0.84 | KDM4E (0.79) | KDM4EHSD17B10ALDH1A1HPGDMAPK1 | |
| SCHEMBL7788538 | 0.83 | KDM4E (0.49) | KDM4EHSD17B10ALDH1A1HPGDMAPK1 | |
| SCHEMBL17908028 | 0.83 | MRGPRX4 (0.53) | KDM4EHSD17B10ALDH1A1HPGDMAPK1 | |
| SCHEMBL18000031 | 0.83 | KDM4E (0.58) | KDM4EHSD17B10ALDH1A1HPGDMAPK1 | |
| SCHEMBL9153858 | 0.83 | KDM4E (0.58) | KDM4EHSD17B10ALDH1A1HPGDMAPK1 | |
| SCHEMBL27673818 | 0.83 | KDM4E (0.58) | KDM4EHSD17B10ALDH1A1HPGDMAPK1 | |
| SCHEMBL5176500 | 0.83 | KDM4E (0.62) | KDM4EHSD17B10ALDH1A1HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1147074-A1 | SYNTHESIS METHOD OF NITROXYMETHYLPHENYL ESTERS OF ASPIRIN DERIVATIVES | NICOX S.A. (FR) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000044705-A1 | SYNTHESIS METHOD OF NITROXYMETHYLPHENYL ESTERS OF ASPIRIN DERIVATIVES | NICOX S.A. (FR) | 2000-08-03 | — | — | WO | disclosed |