Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CCR1 | P32246 | 3/20 | 0.45 |
| ▸ | CCR5 | P51681 | 3/20 | 0.45 |
| ▸ | CCR8 | P51685 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30074397 | 0.91 | CCR1 (0.53) | TP53PKMMEN1KMT2ACCR1 | |
| SCHEMBL31517145 | 0.89 | CCR1 (0.55) | TP53PKMMEN1KMT2ACCR1 | |
| SCHEMBL700298 | 0.89 | CCR1 (0.55) | TP53PKMMEN1KMT2ACCR1 | |
| Hydrochloric Acid SCHEMBL9225985 | 0.88 | CCR1 (0.53) | TP53PKMMEN1KMT2ACCR1 | |
| SCHEMBL23609564 | 0.84 | TP53 (0.52) | TP53PKMMEN1KMT2ACCR1 | |
| SCHEMBL2986171 | 0.84 | MEN1 (0.60) | TP53PKMMEN1KMT2ACCR1 | |
| SCHEMBL22761519 | 0.81 | CCR1 (0.50) | TP53PKMMEN1KMT2ACCR1 | |
| SCHEMBL13311187 | 0.81 | CCR1 (0.64) | TP53PKMKMT2ACCR1CCR5 | |
| SCHEMBL29660049 | 0.81 | CCR1 (0.64) | TP53PKMKMT2ACCR1CCR5 | |
| SCHEMBL2007559 | 0.81 | CCR1 (0.64) | TP53PKMKMT2ACCR1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1155025-A1 | PLATINUM (II) COMPOUNDS | ISIS INNOVATION LIMITED (GB) | 2001-11-21 | — | — | EP | claimed |
| WO-2000050431-A1 | PLATINUM (II) COMPOUNDS | ISIS INNOVATION LIMITED (GB) | 2000-08-31 | — | — | WO | claimed |