Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 5/20 | 0.67 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.67 |
| ▸ | CCR1 | P32246 | 3/20 | 0.50 |
| ▸ | CCR5 | P51681 | 3/20 | 0.50 |
| ▸ | CCR8 | P51685 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | ALPI | P09923 | 1/20 | 0.48 |
| ▸ | ALPG | P10696 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7784900 | 0.94 | CYP1A2 (0.59) | CYP2D6CYP19A1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL9676963 | 0.94 | CYP1A2 (0.59) | CYP2D6CYP19A1CYP2C9CYP2C19CYP1A2 | |
| Hydrochloric Acid SCHEMBL9679292 | 0.92 | CYP1A2 (0.57) | CYP2D6CYP19A1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL13596182 | 0.92 | CYP1A2 (0.55) | CYP2D6CYP19A1CYP2C9CYP2C19CYP1A2 | |
| 2-Mercaptopyridine SCHEMBL7790795 | 0.90 | CYP2D6 (0.56) | CYP2D6CYP19A1CYP2C9CYP2C19CYP1A2 | |
| 2-Mercaptopyridine SCHEMBL7793820 | 0.90 | CYP2D6 (0.56) | CYP2D6CYP19A1CYP2C9CYP2C19CYP1A2 | |
| 2-Mercaptoethanol SCHEMBL7795196 | 0.89 | CYP2D6 (0.55) | CYP2D6CYP19A1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL15457392 | 0.86 | CYP2D6 (0.57) | CYP2D6CYP19A1CYP2C9CYP2C19CYP1A2 | |
| 2-Mercaptopyridine SCHEMBL7793832 | 0.85 | CYP1A2 (0.50) | CYP2D6CYP19A1CYP2C9CYP2C19CYP1A2 | |
| 2-Mercaptopyridine SCHEMBL7793904 | 0.85 | CYP1A2 (0.50) | CYP2D6CYP19A1CYP2C9CYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3240833-B1 | LUMINESCENT SILICONE COATINGS | MOMENTIVE PERFORMANCE MAT INC (US) | 2020-06-03 | — | — | EP | disclosed |
| EP-1155025-A1 | PLATINUM (II) COMPOUNDS | ISIS INNOVATION LIMITED (GB) | 2001-11-21 | — | — | EP | disclosed |
| WO-2000050431-A1 | PLATINUM (II) COMPOUNDS | ISIS INNOVATION LIMITED (GB) | 2000-08-31 | — | — | WO | disclosed |