SCHEMBL7791259

SCHEMBL7791259

CCCCc1ccc(-c2ccc(C=NN=Cc3ccc(C)cc3)cc2F)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 4/20 0.46
GRIN2D O15399 1/20 0.46
GRIN3B O60391 1/20 0.46
GRIN1 Q05586 1/20 0.46
GRIN2A Q12879 1/20 0.46
GRIN2B Q13224 1/20 0.46
GRIN2C Q14957 1/20 0.46
GRIN3A Q8TCU5 1/20 0.46
NPC1 O15118 3/20 0.41
RAB9A P51151 3/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
S1PR1 P21453 3/20 0.36
S1PR3 Q99500 2/20 0.36
RARA P10276 1/20 0.36
RARG P13631 1/20 0.36
TP53 P04637 1/20 0.36
POLB P06746 1/20 0.36
NFKB1 P19838 1/20 0.36
MAPK1 P28482 1/20 0.36
NFKB2 Q00653 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7789214 0.96 RARB (0.51) RARBGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL7791549 0.95 RARB (0.53) RARBGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL7791132 0.95 RARB (0.53) RARBGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL7791383 0.93 NPC1 (0.44) RARBGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL7788994 0.93 RARB (0.48) RARBGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL7788308 0.93 NPC1 (0.44) RARBGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL7793521 0.91 RARB (0.47) RARBGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL7792616 0.89 RARB (0.53) RARBGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL7783215 0.88 RARB (0.55) RARBGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL7793514 0.88 RARB (0.55) RARBGRIN2DGRIN3BGRIN1GRIN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0825176-B1 Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same DAINIPPON INK & CHEMICALS (JP) 2001-11-14 EP disclosed
US-6010642-A LIGHT SCATTERING LIQUID CRYSTAL DISPLAY DAINIPPON INK AND CHEMICALS, INC. (JP) 2000-01-04 US disclosed
EP-0825176-A1 Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same DAINIPPON INK AND CHEMICALS, INC. (JP) 1998-02-25 EP disclosed