SCHEMBL7791271

SCHEMBL7791271

C=CCOc1c(F)cc(C=NN=Cc2ccc(CC)cc2)cc1F

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 5/20 0.38
LMNA P02545 4/20 0.38
HSD17B10 Q99714 1/20 0.36
HPGD P15428 2/20 0.35
TLR4 O00206 1/20 0.35
NPC1 O15118 4/20 0.34
RAB9A P51151 4/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
TUBB1 Q9H4B7 2/20 0.34
TP53 P04637 1/20 0.34
MAOA P21397 1/20 0.33
GAA P10253 3/20 0.33
PKM P14618 1/20 0.33
MAPT P10636 2/20 0.32
KDM4E B2RXH2 1/20 0.32
POLB P06746 1/20 0.32
HTT P42858 1/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7791268 1.00 SMN1; SMN2 (0.38) SMN1; SMN2LMNAHSD17B10HPGDTLR4
SCHEMBL7791168 0.90 SMN1; SMN2 (0.37) SMN1; SMN2LMNAHSD17B10HPGDTLR4
SCHEMBL7791166 0.90 SMN1; SMN2 (0.37) SMN1; SMN2LMNAHSD17B10HPGDTLR4
SCHEMBL7788982 0.88 GRIN2D (0.45) SMN1; SMN2LMNAHSD17B10HPGDTLR4
SCHEMBL7788980 0.88 GRIN2D (0.45) SMN1; SMN2LMNAHSD17B10HPGDTLR4
SCHEMBL7791469 0.87 GRIN2D (0.41) SMN1; SMN2LMNAHSD17B10MEN1KMT2A
SCHEMBL7791472 0.87 GRIN2D (0.41) SMN1; SMN2LMNAHSD17B10MEN1KMT2A
SCHEMBL7791909 0.86 NPC1 (0.47) SMN1; SMN2LMNAHSD17B10TLR4NPC1
SCHEMBL7791906 0.86 NPC1 (0.47) SMN1; SMN2LMNAHSD17B10TLR4NPC1
SCHEMBL7783275 0.86 MEN1 (0.42) SMN1; SMN2LMNAHSD17B10HPGDNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0825176-B1 Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same DAINIPPON INK & CHEMICALS (JP) 2001-11-14 EP disclosed
US-6010642-A LIGHT SCATTERING LIQUID CRYSTAL DISPLAY DAINIPPON INK AND CHEMICALS, INC. (JP) 2000-01-04 US disclosed
EP-0825176-A1 Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same DAINIPPON INK AND CHEMICALS, INC. (JP) 1998-02-25 EP disclosed