Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.41 |
| ▸ | RRM1 | P23921 | 1/20 | 0.36 |
| ▸ | TRPM2 | O94759 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 3/20 | 0.34 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7791875 | 1.00 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2GRIN2DGRIN3B | |
| SCHEMBL7789231 | 0.99 | NPC1 (0.45) | NPC1RAB9ASMN1; SMN2GRIN2DGRIN3B | |
| SCHEMBL7789233 | 0.99 | NPC1 (0.45) | NPC1RAB9ASMN1; SMN2GRIN2DGRIN3B | |
| SCHEMBL7783266 | 0.96 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2GRIN2DGRIN3B | |
| SCHEMBL7783270 | 0.96 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2GRIN2DGRIN3B | |
| SCHEMBL7783249 | 0.90 | GRIN2D (0.42) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL7783252 | 0.90 | GRIN2D (0.42) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL7788723 | 0.90 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2GRIN2DGRIN3B | |
| SCHEMBL7788722 | 0.90 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2GRIN2DGRIN3B | |
| SCHEMBL7791246 | 0.89 | GRIN2D (0.44) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825176-B1 | Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same | DAINIPPON INK & CHEMICALS (JP) | 2001-11-14 | — | — | EP | disclosed |
| US-6010642-A | LIGHT SCATTERING LIQUID CRYSTAL DISPLAY | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0825176-A1 | Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1998-02-25 | — | — | EP | disclosed |