Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.66 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.58 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | DNA2 | P51530 | 1/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
| ▸ | CTSD | P07339 | 1/20 | 0.47 |
| ▸ | DTYMK | P23919 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3671 | 0.98 | TSHR (0.68) | TSHRGPR35APEX1TDP1L3MBTL1 | |
| SCHEMBL30893562 | 0.98 | TSHR (0.68) | TSHRGPR35APEX1TDP1L3MBTL1 | |
| SCHEMBL28208709 | 0.96 | TSHR (0.66) | TSHRGPR35APEX1TDP1L3MBTL1 | |
| SCHEMBL16267318 | 0.96 | TSHR (0.66) | TSHRGPR35APEX1TDP1L3MBTL1 | |
| Ammonia Solution, Strong SCHEMBL28168558 | 0.96 | TSHR (0.66) | TSHRGPR35APEX1TDP1L3MBTL1 | |
| Potassium Ion SCHEMBL16267317 | 0.96 | TSHR (0.66) | TSHRGPR35APEX1TDP1L3MBTL1 | |
| Hydrogen Sulfide SCHEMBL27504969 | 0.96 | TSHR (0.66) | TSHRGPR35APEX1TDP1L3MBTL1 | |
| SCHEMBL10824707 | 0.96 | TSHR (0.66) | TSHRGPR35APEX1TDP1L3MBTL1 | |
| Lithium Ion SCHEMBL7791976 | 0.96 | TSHR (0.66) | TSHRGPR35APEX1TDP1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL1901670 | 0.96 | TSHR (0.66) | TSHRGPR35APEX1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8105899-A | — | — | None | — | — | JP | disclosed |
| EP-0703453-B1 | Method for the determination of creatinine and urinary protein | BAYER AG (US) | 2001-11-07 | — | — | EP | disclosed |
| EP-0703453-A1 | Dry reagent for creatinine assay | Bayer Corporation (US) | 1996-03-27 | — | — | EP | disclosed |
| US-5464777-A | Dry reagent for creatinine assay | MILES INC. (US) | 1995-11-07 | — | — | US | disclosed |