Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7783289 | 1.00 | KMT2A (0.57) | KMT2ATSHRHTR2AHTR2CHTR2B | |
| SCHEMBL7783284 | 1.00 | KMT2A (0.57) | KMT2ATSHRHTR2AHTR2CHTR2B | |
| Fenoprop SCHEMBL2419073 | 0.87 | TSHR (0.56) | KMT2ATSHRHTR2AHTR2CHTR2B | |
| Fenoprop SCHEMBL29385175 | 0.87 | TSHR (0.56) | KMT2ATSHRHTR2AHTR2CHTR2B | |
| Fenoprop SCHEMBL29397851 | 0.87 | TSHR (0.56) | KMT2ATSHRHTR2AHTR2CHTR2B | |
| Fenoprop SCHEMBL5053997 | 0.87 | TSHR (0.56) | KMT2ATSHRHTR2AHTR2CHTR2B | |
| Fenoprop SCHEMBL55790 | 0.87 | TSHR (0.56) | KMT2ATSHRHTR2AHTR2CHTR2B | |
| Fenoprop SCHEMBL25437012 | 0.86 | TSHR (0.54) | KMT2ATSHRHTR2AHTR2CHTR2B | |
| Fenoprop SCHEMBL11690135 | 0.86 | TSHR (0.54) | KMT2ATSHRHTR2AHTR2CHTR2B | |
| Fenoprop SCHEMBL29729480 | 0.83 | TSHR (0.51) | KMT2ATSHRHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850246-B1 | PYRIMIDINE NUCLEOSIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2001-11-14 | — | — | EP | disclosed |
| EP-0850246-A2 | PYRIMIDINE NUCLEOSIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1998-07-01 | — | — | EP | disclosed |
| US-5705492-A | ESTERIFICATION OF PYRIMIDINE NUCLEOSIDE | HOFFMANN-LA ROCHE INC. (US) | 1998-01-06 | — | — | US | disclosed |
| WO-1997003082-A2 | PYRIMIDINE NUCLEOSIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1997-01-30 | — | — | WO | disclosed |