SCHEMBL7792437

SCHEMBL7792437

CCc1ccc(/C=N/N=C/c2cc(F)c(OC)c(F)c2)cc1

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TUBB1 Q9H4B7 7/20 0.48
MAPT P10636 3/20 0.37
CYP1A2 P05177 1/20 0.37
MAOA P21397 1/20 0.37
KMT2A Q03164 3/20 0.37
GAA P10253 3/20 0.37
PTGS2 P35354 1/20 0.36
CHRM5 P08912 1/20 0.36
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
MEN1 O00255 2/20 0.35
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
PKM P14618 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7792440 1.00 TUBB1 (0.48) TUBB1MAPTCYP1A2MAOAKMT2A
SCHEMBL7793533 0.88 GRIN2D (0.40) TUBB1MAPTCYP1A2KMT2AGAA
SCHEMBL7793531 0.88 GRIN2D (0.40) TUBB1MAPTCYP1A2KMT2AGAA
SCHEMBL7783458 0.87 TUBB1 (0.38) TUBB1MAPTCYP1A2MAOAKMT2A
SCHEMBL7783454 0.87 TUBB1 (0.38) TUBB1MAPTCYP1A2MAOAKMT2A
SCHEMBL7791188 0.86 GRIN2D (0.50) TUBB1MAPTCYP1A2KMT2AGAA
SCHEMBL7791185 0.86 GRIN2D (0.50) TUBB1MAPTCYP1A2KMT2AGAA
SCHEMBL7791267 0.85 GRIN2D (0.46) PTGS2CHRM5ALDH1A1LMNA
SCHEMBL7791263 0.85 GRIN2D (0.46) PTGS2CHRM5ALDH1A1LMNA
SCHEMBL7783520 0.84 TUBB1 (0.35) TUBB1MAPTMAOAKMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0825176-B1 Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same DAINIPPON INK & CHEMICALS (JP) 2001-11-14 EP disclosed
US-6010642-A LIGHT SCATTERING LIQUID CRYSTAL DISPLAY DAINIPPON INK AND CHEMICALS, INC. (JP) 2000-01-04 US disclosed
EP-0825176-A1 Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same DAINIPPON INK AND CHEMICALS, INC. (JP) 1998-02-25 EP disclosed