SCHEMBL7792585

SCHEMBL7792585

CCc1ccc(/C=N/N=C\c2ccc(OC(F)F)c(F)c2)cc1

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38
MAPT P10636 2/20 0.37
CYP1A2 P05177 1/20 0.37
TUBB1 Q9H4B7 5/20 0.35
LMNA P02545 4/20 0.34
ALDH1A1 P00352 2/20 0.34
MAOA P21397 1/20 0.34
GAA P10253 2/20 0.33
PKM P14618 2/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
HTT P42858 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
MITF O75030 1/20 0.33
POLB P06746 1/20 0.33
MAPK1 P28482 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7792588 1.00 KMT2A (0.38) KMT2AMEN1MAPTCYP1A2TUBB1
SCHEMBL7788319 0.90 GRIN2D (0.36) KMT2AMEN1MAPTCYP1A2TUBB1
SCHEMBL7788317 0.90 GRIN2D (0.36) KMT2AMEN1MAPTCYP1A2TUBB1
SCHEMBL7792550 0.87 GRIN2D (0.46) KMT2AMEN1MAPTCYP1A2TUBB1
SCHEMBL7792546 0.87 GRIN2D (0.46) KMT2AMEN1MAPTCYP1A2TUBB1
SCHEMBL7793471 0.86 GRIN2D (0.42) KMT2AMEN1MAPTCYP1A2LMNA
SCHEMBL7793474 0.86 GRIN2D (0.42) KMT2AMEN1MAPTCYP1A2LMNA
SCHEMBL7788221 0.85 GRIN2D (0.41) LMNAALDH1A1
SCHEMBL7788217 0.85 GRIN2D (0.41) LMNAALDH1A1
SCHEMBL7783520 0.85 TUBB1 (0.35) KMT2AMEN1MAPTTUBB1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0825176-B1 Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same DAINIPPON INK & CHEMICALS (JP) 2001-11-14 EP disclosed
US-6010642-A LIGHT SCATTERING LIQUID CRYSTAL DISPLAY DAINIPPON INK AND CHEMICALS, INC. (JP) 2000-01-04 US disclosed
EP-0825176-A1 Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same DAINIPPON INK AND CHEMICALS, INC. (JP) 1998-02-25 EP disclosed