SCHEMBL7793058

SCHEMBL7793058

CCc1ccc(/C=N/N=C\c2ccc(OC(F)(F)F)c(F)c2)cc1

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
PDE2A O00408 3/20 0.37
CYP1A2 P05177 1/20 0.37
MAPT P10636 1/20 0.37
EPHX2 P34913 1/20 0.37
TUBB1 Q9H4B7 3/20 0.35
MAOA P21397 1/20 0.34
GCGR P47871 1/20 0.34
HCRTR1 O43613 5/20 0.34
HCRTR2 O43614 5/20 0.34
NPC1 O15118 1/20 0.33
GAA P10253 1/20 0.33
PKM P14618 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7793062 1.00 MEN1 (0.38) MEN1KMT2APDE2ACYP1A2MAPT
SCHEMBL7783567 0.90 GRIN2D (0.36) MEN1KMT2APDE2ACYP1A2MAPT
SCHEMBL7783568 0.90 GRIN2D (0.36) MEN1KMT2APDE2ACYP1A2MAPT
SCHEMBL7789284 0.87 GRIN2D (0.46) MEN1KMT2APDE2ACYP1A2MAPT
SCHEMBL7789285 0.87 GRIN2D (0.46) MEN1KMT2APDE2ACYP1A2MAPT
SCHEMBL7793153 0.86 GRIN2D (0.42) MEN1KMT2APDE2ACYP1A2MAPT
SCHEMBL7793150 0.86 GRIN2D (0.42) MEN1KMT2APDE2ACYP1A2MAPT
SCHEMBL7792401 0.85 GRIN2D (0.41)
SCHEMBL7792397 0.85 GRIN2D (0.41)
SCHEMBL7783454 0.85 TUBB1 (0.38) MEN1KMT2APDE2ACYP1A2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0825176-B1 Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same DAINIPPON INK & CHEMICALS (JP) 2001-11-14 EP disclosed
US-6010642-A LIGHT SCATTERING LIQUID CRYSTAL DISPLAY DAINIPPON INK AND CHEMICALS, INC. (JP) 2000-01-04 US disclosed
EP-0825176-A1 Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same DAINIPPON INK AND CHEMICALS, INC. (JP) 1998-02-25 EP disclosed