Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7793576 | 1.00 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2GRIN2DGRIN3B | |
| SCHEMBL7783385 | 0.95 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2GRIN2DGRIN3B | |
| SCHEMBL7783388 | 0.95 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2GRIN2DGRIN3B | |
| SCHEMBL7789052 | 0.92 | GRIN2D (0.44) | NPC1RAB9ASMN1; SMN2GRIN2DGRIN3B | |
| SCHEMBL7789049 | 0.92 | GRIN2D (0.44) | NPC1RAB9ASMN1; SMN2GRIN2DGRIN3B | |
| SCHEMBL7788629 | 0.89 | NPC1 (0.59) | NPC1RAB9ASMN1; SMN2GRIN2DGRIN3B | |
| SCHEMBL7788626 | 0.89 | NPC1 (0.59) | NPC1RAB9ASMN1; SMN2GRIN2DGRIN3B | |
| SCHEMBL7788735 | 0.88 | GRIN2D (0.52) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL7791274 | 0.88 | GRIN2D (0.46) | NPC1RAB9ASMN1; SMN2GRIN2DGRIN3B | |
| SCHEMBL7791279 | 0.88 | GRIN2D (0.46) | NPC1RAB9ASMN1; SMN2GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825176-B1 | Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same | DAINIPPON INK & CHEMICALS (JP) | 2001-11-14 | — | — | EP | disclosed |
| EP-0825176-A1 | Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1998-02-25 | — | — | EP | disclosed |