SCHEMBL7793670

SCHEMBL7793670

O=Cc1cccc(-c2cc(C(=O)O)cc(C(=O)O)c2)c1

nearest known ligand 0.75

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TRIM24 O15164 1/20 0.75
TRIM33 Q9UPN9 1/20 0.75
UNG P13051 1/20 0.65
DHODH Q02127 6/20 0.56
KMO O15229 1/20 0.52
ERN1 O75460 4/20 0.51
RXRA P19793 2/20 0.50
RXRB P28702 2/20 0.50
ALDH1A1 P00352 2/20 0.47
KDM4E B2RXH2 1/20 0.46
POLB P06746 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA9 Q16790 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2587878 0.91 UNG (0.79) TRIM24TRIM33UNGKMOERN1
SCHEMBL29952036 0.91 UNG (0.79) TRIM24TRIM33UNGKMOERN1
SCHEMBL2555482 0.90 TRIM24 (0.67) TRIM24TRIM33UNGDHODHKMO
SCHEMBL2559724 0.89 TRIM24 (0.65) TRIM24TRIM33UNGDHODHKMO
SCHEMBL2563676 0.89 TRIM24 (0.65) TRIM24TRIM33UNGDHODHKMO
SCHEMBL2554588 0.89 TRIM24 (0.65) TRIM24TRIM33UNGDHODHKMO
SCHEMBL12152644 0.86 TRIM24 (1.00) TRIM24TRIM33UNGKMOERN1
SCHEMBL2559790 0.85 TRIM24 (0.60) TRIM24TRIM33UNGDHODHKMO
SCHEMBL2560257 0.85 TRIM24 (0.60) TRIM24TRIM33UNGERN1RXRA
SCHEMBL15330304 0.84 TRIM24 (0.58) TRIM24TRIM33UNGERN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2001335556-A METHOD FOR PRODUCING 5-(3-CYANOPHENYL)-3-FORMYLBENZOIC ACID DERIVATIVE TEIJIN LTD 2001-12-04 JP disclosed