SCHEMBL7793703

SCHEMBL7793703

Clc1ccc2c(c1)[CH]C=C2

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 2/20 0.36
TSHR P16473 7/20 0.33
CYP3A4 P08684 5/20 0.33
ALDH1A1 P00352 3/20 0.33
TDP1 Q9NUW8 3/20 0.33
CYP2A6 P11509 2/20 0.33
ALOX15 P16050 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
LMNA P02545 1/20 0.33
F7 P08709 1/20 0.33
F3 P13726 1/20 0.33
DYRK1A Q13627 1/20 0.33
HSD17B10 Q99714 3/20 0.32
AHR P35869 1/20 0.32
MAPK1 P28482 3/20 0.31
S100A4 P26447 1/20 0.31
HTR2C P28335 1/20 0.31
VCAM1 P19320 1/20 0.31
HPGD P15428 1/20 0.30
ALOX12 P18054 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7794695 0.90 TP53 (0.36) TP53TSHRCYP3A4ALDH1A1TDP1
SCHEMBL7799447 0.78
SCHEMBL5004042 0.70 AHR (0.32) AHRMAPK1
SCHEMBL7784962 0.70 CA12 (0.34) ALDH1A1TDP1CYP2A6ALOX15AHR
SCHEMBL27338971 0.65 CA12 (0.39)
SCHEMBL1875062 0.64 CES1 (0.33) TP53AHR
SCHEMBL6832707 0.64 HTR2A (0.35) TP53LMNAF7F3AHR
SCHEMBL6832591 0.64 HTR2A (0.35) TP53CYP3A4LMNAAHRHTR2C
SCHEMBL1447891 0.64 TP53 (0.31) TP53
SCHEMBL22982710 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1155698-A1 ORGANOBORON COMPOUNDS EXHIBITING ANTICOCCIDIAL ACTIVITIES Nitto Kasei Co., Ltd. (JP) 2001-11-21 EP disclosed