SCHEMBL77938

SCHEMBL77938

CC(C)(c1ccccc1)c1ccc(OC(c2ccc(C(C)(C)c3ccccc3)cc2C(C)(C)c2ccccc2)C(CO)(CO)CO)c(C(C)(C)c2ccccc2)c1

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.36
KMT2A Q03164 6/20 0.36
ALDH1A1 P00352 6/20 0.36
MEN1 O00255 5/20 0.36
ESR1 P03372 2/20 0.36
ESR2 Q92731 2/20 0.36
LMNA P02545 2/20 0.36
POLB P06746 2/20 0.36
CYP3A4 P08684 1/20 0.36
SMN1; SMN2 Q16637 3/20 0.35
TDP1 Q9NUW8 1/20 0.33
HTT P42858 2/20 0.33
CNR1 P21554 2/20 0.33
CNR2 P34972 2/20 0.33
GAA P10253 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5598652 0.96 KDM4E (0.34) KDM4EKMT2AALDH1A1MEN1ESR1
SCHEMBL6837322 0.96 KDM4E (0.34) KDM4EKMT2AALDH1A1MEN1ESR1
SCHEMBL190544 0.96 KDM4E (0.34) KDM4EKMT2AALDH1A1MEN1ESR1
SCHEMBL4302020 0.94 CYP2C19 (0.34) KDM4EKMT2AALDH1A1MEN1ESR1
SCHEMBL4305432 0.92 KDM4E (0.35) KDM4EKMT2AALDH1A1MEN1ESR1
SCHEMBL28643112 0.92 KDM4E (0.33) KDM4EKMT2AALDH1A1MEN1ESR1
Pyrophosphoric Acid SCHEMBL374861 0.92 KDM4E (0.33) KDM4EKMT2AALDH1A1MEN1ESR1
SCHEMBL16876756 0.91 CYP1A2 (0.32) KDM4EKMT2AMEN1LMNAPOLB
SCHEMBL29027349 0.90 KDM4E (0.32) KDM4EKMT2AALDH1A1MEN1ESR1
SCHEMBL236804 0.89 KMT2A (0.31) KDM4EKMT2AALDH1A1MEN1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5558 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12595354-B2 Method for the manufacture of a polycarbonate composition SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2026-04-07 US claimed
CN-118325072-A Preparation method and application of low-rheological and low-yellowing nylon 中国石油化工股份有限公司 2024-07-12 CN claimed
US-20240218131-A1 A MASTERBATCH FOR UPGRADING POLYESTERS NEXAM CHEMICAL AB (SE) 2024-07-04 US claimed
CN-118256026-A Anti-aging composition, high-temperature-resistant polyamide compound and preparation method thereof 天津利安隆新材料股份有限公司 2024-06-28 CN claimed
CN-118222220-A Photovoltaic packaging material and preparation method thereof 浙江利昌科技有限公司 2024-06-21 CN claimed
US-20240174800-A1 MELT-STABLE POLYLACTIDE RESIN COMPOSITIONS CONTAINING PHOSPHITE ESTERS NATUREWORKS LLC 2024-05-30 US claimed
CN-115304912-B Polyamide composite material and preparation method and application thereof 江苏金发科技新材料有限公司 2024-05-28 CN claimed
CN-118063895-A Extrusion-blowing transparent polypropylene resin and preparation method thereof 中国神华煤制油化工有限公司 2024-05-24 CN claimed
CN-118063957-A Flexible hydrolysis-resistant extrusion polyamide material, preparation method thereof and nylon tube 山东祥龙新材料股份有限公司 2024-05-24 CN claimed
CN-118047910-A Polyglycolic acid grafted polymer and preparation method and application thereof 中国石油化工股份有限公司 2024-05-17 CN claimed
EP-1172405-A1 Rubber compositions containing a trivalent phosphorous compound-silica complex THE GOODYEAR TIRE & RUBBER COMPANY (US) 2002-01-16 EP claimed
WO-2001098402-A1 POLYCARBONATE COMPOSITION WITH REDUCED MOLD DEPOSITS GENERAL ELECTRIC COMPANY (US) 2001-12-27 WO claimed
EP-1151034-A1 PHOSPHITE ADDITIVES IN POLYOLEFINS Phillips Petroleum Company (US) 2001-11-07 EP claimed
WO-2001077206-A1 PROCESS FOR REDISTRIBUTION OF POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2001-10-18 WO claimed
US-20010023270-A1 Phosphite stabilizing composition and method STEIN DARYL L (US) 2001-09-20 US claimed
EP-1115783-A1 NOVEL POLYPROPYLENE COMPOSITIONS UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 2001-07-18 EP claimed
US-6224791-B1 PHENYLBENZOFURAN-2-ONE WITH PHOSPHITE DOVER CHEMICAL CORPORATION 2001-05-01 US claimed
WO-2000023514-A1 PHOSPHITE ADDITIVES IN POLYOLEFINS PHILLIPS PETROLEUM COMPANY (US) 2000-04-27 WO claimed
WO-2000012605-A1 NOVEL POLYPROPYLENE COMPOSITIONS UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 2000-03-09 WO claimed
WO-1999003915-A1 LACTONE/PHOSPHITE BLENDS DOVER CHEMICAL CORPORATION (US) 1999-01-28 WO claimed