Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.46 |
| ▸ | PTPRC | P08575 | 1/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 2/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.35 |
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2761886 | 0.82 | ADORA1 (0.63) | ADORA1PTPRCPTPN2PTPN1ALOX15 | |
| SCHEMBL1175495 | 0.80 | PTPRC (0.48) | ADORA1PTPRCPTPN2PTPN1APEX1 | |
| SCHEMBL9137624 | 0.77 | CHRM5 (0.37) | ADORA1PTPRCPTPN2PTPN1PNMT | |
| SCHEMBL7790171 | 0.72 | ADORA1 (0.45) | ADORA1PTPRCPTPN2PTPN1APEX1 | |
| SCHEMBL13354793 | 0.72 | ADORA1 (0.37) | ADORA1HSD17B10 | |
| SCHEMBL7796179 | 0.72 | ADORA1 (0.45) | ADORA1PTPRCPTPN2PTPN1APEX1 | |
| SCHEMBL30772840 | 0.71 | PTPRC (0.60) | ADORA1PTPRCPTPN2PTPN1APEX1 | |
| SCHEMBL31329755 | 0.71 | CXCR2 (0.53) | ADORA1PTPRCPTPN2PTPN1APEX1 | |
| SCHEMBL30477005 | 0.70 | ADORA1 (0.63) | ADORA1PTPRCPTPN2PTPN1CXCR2 | |
| Hydrochloric Acid SCHEMBL28923959 | 0.69 | ADORA1 (0.64) | ADORA1PTPRCPTPN2PTPN1CXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010151317-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2010-12-29 | — | — | WO | disclosed |