Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MKNK1 | Q9BUB5 | 10/20 | 0.46 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.45 |
| ▸ | FABP4 | P15090 | 1/20 | 0.44 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7796802 | 0.86 | ADORA1 (0.63) | ADORA1KDM4EMAPTMKNK1P2RX3 | |
| SCHEMBL7794276 | 0.86 | ADORA1 (0.63) | ADORA1KDM4EMAPTMKNK1P2RX3 | |
| SCHEMBL12869122 | 0.84 | ADORA1 (0.68) | ADORA1KDM4EMAPTMKNK1 | |
| SCHEMBL27302182 | 0.81 | ADORA1 (0.77) | ADORA1KDM4EMAPTMKNK1P2RX3 | |
| SCHEMBL6425010 | 0.80 | ADORA1 (0.55) | ADORA1KDM4EMAPTMKNK1P2RX3 | |
| SCHEMBL3499018 | 0.79 | ADORA1 (1.00) | ADORA1KDM4EMAPTMKNK1P2RX3 | |
| SCHEMBL9139042 | 0.78 | ADORA1 (0.47) | ADORA1KDM4EMAPTMKNK1P2RX3 | |
| SCHEMBL741444 | 0.77 | ADORA1 (0.55) | ADORA1KDM4EMAPTP2RX3FABP4 | |
| SCHEMBL7796803 | 0.77 | ADORA1 (0.55) | ADORA1KDM4EMAPTMKNK1P2RX3 | |
| SCHEMBL7794277 | 0.77 | ADORA1 (0.55) | ADORA1KDM4EMAPTMKNK1P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010151317-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2010-12-29 | — | — | WO | disclosed |