Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 15/20 | 0.62 |
| ▸ | RARB | P10826 | 10/20 | 0.62 |
| ▸ | RARA | P10276 | 9/20 | 0.62 |
| ▸ | RXRA | P19793 | 2/20 | 0.50 |
| ▸ | PTPRC | P08575 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5846651 | 0.90 | RARG (0.80) | RARGRARBRARARXRA | |
| SCHEMBL7789708 | 0.87 | RARG (0.59) | RARGRARBRARARXRAPTPRC | |
| SCHEMBL5845709 | 0.83 | RARG (0.60) | RARGRARBRARARXRAPDK2 | |
| SCHEMBL6730349 | 0.81 | RARB (0.61) | RARGRARBRARARXRAPDK2 | |
| SCHEMBL4965729 | 0.79 | RARB (0.69) | RARGRARBRARARXRA | |
| SCHEMBL7265434 | 0.79 | RARG (0.56) | RARGRARBRARARXRA | |
| SCHEMBL2915270 | 0.79 | RARG (0.69) | RARGRARBRARARXRA | |
| SCHEMBL2945148 | 0.78 | RARG (0.55) | RARGRARBRARARXRA | |
| SCHEMBL5846170 | 0.78 | RARB (0.60) | RARGRARBRARARXRAPDK2 | |
| SCHEMBL7794229 | 0.78 | RARB (0.75) | RARGRARBRARARXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0952974-B1 | BIPHENYL DERIVATIVES SUBSTITUTED BY AN AROMATIC OR HETEROAROMATIC RADICAL AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME | GALDERMA RES & DEV (FR) | 2001-11-21 | — | — | EP | claimed |