Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 13/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7794934 | 1.00 | HCAR2 (0.53) | HCAR2ATMTSHRTP53EGLN1 | |
| SCHEMBL7794924 | 0.92 | ATM (0.43) | HCAR2ATMMAPTRAB9ANPSR1 | |
| SCHEMBL9576224 | 0.92 | ATM (0.43) | HCAR2ATMMAPTRAB9ANPSR1 | |
| SCHEMBL9063815 | 0.85 | HCAR2 (0.53) | HCAR2ATMTSHRTP53EGLN1 | |
| SCHEMBL7790959 | 0.85 | HCAR2 (0.53) | HCAR2ATMTSHRTP53EGLN1 | |
| SCHEMBL9063812 | 0.85 | HCAR2 (0.53) | HCAR2ATMTSHRTP53EGLN1 | |
| SCHEMBL7790962 | 0.85 | HCAR2 (0.53) | HCAR2ATMTSHRTP53EGLN1 | |
| SCHEMBL3482387 | 0.81 | HCAR2 (0.59) | HCAR2ATMTSHRMAPTALDH1A1 | |
| SCHEMBL3482379 | 0.81 | HCAR2 (0.59) | HCAR2ATMTSHRMAPTALDH1A1 | |
| SCHEMBL15019408 | 0.80 | HCAR2 (0.59) | HCAR2ATMTSHRTP53EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729041-B1 | Water-Absorptive soft contact lens | MENICON CO LTD (JP) | 2001-11-28 | — | — | EP | disclosed |
| US-5741830-A | COPOLYMER OF A FLUORINE CONTAINING STYRENE DERIVATIVE AND N,N-DIMETHYL(METH)ACRYLAMIDE | MENICON CO., LTD. (JP) | 1998-04-21 | — | — | US | disclosed |
| EP-0729041-A2 | Water-Absorptive soft contact lens | Menicon Co., Ltd. (JP) | 1996-08-28 | — | — | EP | disclosed |
| EP-0524557-B1 | Ocular lens material | MENICON CO LTD (JP) | 1996-01-17 | — | — | EP | disclosed |
| US-5391591-A | A curable additional copolymer molding materials having a styrenic monomer, a hydrophilic acrylamide monomer and a crosslinkable vinylbenzyl acrylate monomer; permselectivity, tensile strength, low water absorption | MENICON CO., LTD. (JP) | 1995-02-21 | — | — | US | disclosed |
| US-5250583-A | Polymer of fluoroalkyl silicon-containing alkyl fumarate, N-vinyllactam, acrylic or methacrylic acid, crosslinkable monomer | MENICON CO., LTD. (JP) | 1993-10-05 | — | — | US | disclosed |
| EP-0524557-A2 | Ocular lens material | Menicon Co., Ltd. (JP) | 1993-01-27 | — | — | EP | disclosed |