⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4441989 | 1.00 | — | — | |
| SCHEMBL8749889 | 0.83 | — | — | |
| SCHEMBL114835 | 0.83 | — | — | |
| SCHEMBL13279121 | 0.79 | — | — | |
| SCHEMBL28741281 | 0.77 | — | — | |
| Chloromethane SCHEMBL8156084 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL9581202 | 0.74 | — | — | |
| SCHEMBL6652609 | 0.74 | — | — | |
| SCHEMBL6856964 | 0.74 | — | — | |
| SCHEMBL5829905 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024044549-A1 | VHH ANTIBODY CONJUGATES | Abdera Therapeutics Inc. (US) | 2024-02-29 | — | — | WO | disclosed |
| EP-2739626-B1 | NOVEL SPIROINDOLINE COMPOUNDS | INTERVET INT BV (NL) | 2016-05-04 | — | — | EP | disclosed |
| US-9096599-B2 | Spiroindoline compounds | INTERVET INC. (US) | 2015-08-04 | — | — | US | disclosed |
| US-20140163056-A1 | NOVEL SPIROINDOLINE COMPOUNDS | INTERVET INC. | 2014-06-12 | — | — | US | disclosed |
| EP-2739626-A1 | NOVEL SPIROINDOLINE COMPOUNDS | Intervet International B.V. (NL) | 2014-06-11 | — | — | EP | disclosed |
| WO-2013017678-A1 | NOVEL SPIROINDOLINE COMPOUNDS | INTERVET INTERNATIONAL B.V. (NL) | 2013-02-07 | — | — | WO | disclosed |
| US-6310257-B2 | ACIDOLYSIS OF EPOXIDE COMPOUND TO FORM CYCLOPENTENE DERIVATIVE | NISSAN CHEMICAL INDUSTRIES, LTD (JP) | 2001-10-30 | — | — | US | disclosed |
| US-20010012907-A1 | Substituted cyclopentene derivatives and method for preparing the same | NISSAN CHEMICAL INDUSTRIES, LTD. | 2001-08-09 | — | — | US | disclosed |
| US-6191291-B1 | OXIDATION OF A SUBSTITUTED CYCLOPENTADIENE DERIVATIVE WITH AN OXIDIZING AGENT TO FORM OXIRANE RING CONTAINING SUBSTITUTED CYCLOPENTADIENE DERIVATIVE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2001-02-20 | — | — | US | disclosed |
| US-6025518-A | Substituted cyclopentene derivatives and method for preparing the same | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2000-02-15 | — | — | US | disclosed |
| US-5874634-A | Substituted cyclopentene derivatives and method for preparing the same | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1999-02-23 | — | — | US | disclosed |
| US-5461127-A | Comprising group 4 metal, cyclic hydrocarbon, ligands, Lewis base; addition polymerization | IDEMITSU KOSAN CO., LTD. (JP) | 1995-10-24 | — | — | US | disclosed |