SCHEMBL7795384

SCHEMBL7795384

CCCCCC(c1ccco1)c1ccco1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.43
MEN1 O00255 4/20 0.43
L3MBTL1 Q9Y468 2/20 0.42
HPGD P15428 3/20 0.41
GLA P06280 1/20 0.41
RECQL P46063 1/20 0.41
HDAC3 O15379 1/20 0.39
CYP2C19 P33261 2/20 0.39
ALDH1A1 P00352 3/20 0.38
MAPT P10636 3/20 0.38
NPSR1 Q6W5P4 2/20 0.38
HTT P42858 1/20 0.38
PKM P14618 2/20 0.38
POLB P06746 2/20 0.38
PTPN1 P18031 1/20 0.38
PTPN7 P35236 1/20 0.38
BLM P54132 1/20 0.38
ESR2 Q92731 1/20 0.38
TSHR P16473 1/20 0.37
CSNK1E P49674 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30264728 0.98 KMT2A (0.42) KMT2AMEN1L3MBTL1HPGDGLA
SCHEMBL29013573 0.85 KMT2A (0.46) KMT2AMEN1L3MBTL1HPGDGLA
SCHEMBL8159767 0.82 MEN1 (0.41) KMT2AMEN1HDAC3CSNK1E
SCHEMBL1868809 0.82 KMT2A (0.38) KMT2AMEN1L3MBTL1HPGDGLA
SCHEMBL18934219 0.82 MEN1 (0.41) KMT2AMEN1HDAC3CSNK1E
SCHEMBL2139138 0.82 KMT2A (0.50) KMT2AMEN1L3MBTL1HPGDGLA
SCHEMBL5613043 0.81 KMT2A (0.52) KMT2AMEN1L3MBTL1HDAC3ALDH1A1
SCHEMBL22127720 0.81 KMT2A (0.52) KMT2AMEN1L3MBTL1HDAC3ALDH1A1
SCHEMBL20773076 0.81 KMT2A (0.52) KMT2AMEN1L3MBTL1HDAC3ALDH1A1
SCHEMBL919697 0.81 KMT2A (0.37) KMT2AMEN1L3MBTL1HPGDGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1044226-B1 METHOD FOR COUPLING LIVING CATIONIC POLYMERS DOW CORNING (US) 2001-11-21 EP claimed
EP-1044226-A1 METHOD FOR COUPLING LIVING CATIONIC POLYMERS DOW CORNING CORPORATION (US) 2000-10-18 EP claimed
US-6046281-A REACTING A LIVING CATIONIC POLYMER WITH AN ORGANIC COMPOUND HAVING AT LEAST 2 FURAN RINGS IN ITS MOLECULE, SUCH AS DIFURANYLHEXANE IN THE PRESENCE OF A LEWIS ACID UNIVERSITY OF MASSACHUSETTS LOWELL (US) 2000-04-04 US claimed
WO-1999024480-A1 METHOD FOR COUPLING LIVING CATIONIC POLYMERS DOW CORNING CORPORATION (US) 1999-05-20 WO claimed